Gerber Peter, Anderin Claes, Gustafsson Ulf O, Thorell Anders
Karolinska Institutet, Department of Clinical Sciences, Danderyds Hospital, Stockholm, Sweden; Department of Surgery, Ersta Hospital, Stockholm, Sweden.
Karolinska Institutet, Department of Clinical Sciences, Danderyds Hospital, Stockholm, Sweden; Department of Surgery, Ersta Hospital, Stockholm, Sweden.
Surg Obes Relat Dis. 2016 Mar-Apr;12(3):556-562. doi: 10.1016/j.soard.2015.08.519. Epub 2015 Sep 2.
Weight loss before bariatric surgery has been found to be associated with reduced rates of postoperative complications.
To evaluate whether preoperative weight loss was also associated with improved postoperative weight loss over time and if this was dependent on preoperative body mass index (BMI).
Data from the Swedish national registry for bariatric surgery.
Out of 20,564 patients undergoing primary gastric bypass from January 1, 2008 to November 30, 2011, 9570 with complete data on preoperative weight loss and 2 years postoperative weight loss were analyzed.
Total preoperative weight loss in the 25th, 50th, and 75th percentiles was 0%, 4.5%, and 8.6%, respectively. When comparing patients in the 50th percentile for preoperative weight loss with those in the 25th percentile, total postoperative weight loss was 5.0% and 5.3% higher at 1 and 2 years, respectively (P<.001). Corresponding values for patients in the 75th percentile for preoperative weight loss were 11.8% and 10.1% (P< .001). For patients in the 75th percentile of preoperative BMI (>45.7 kg/m(2)) the effect was even more pronounced. Thus, in this group of patients and within the 75th percentile for preoperative weight loss, the total weight reduction after 1 and 2 years was 15.2% and 13.6% higher compared with patients in the 25th percentile for preoperative weight loss.
In this Swedish national bariatric registry data set, weight loss before gastric bypass was associated with sustained improved postoperative weight reduction. Moreover, there was a relationship between the degree of pre- and postoperative weight loss and the relationship was stronger in patients with high BMI.
已发现减肥手术前的体重减轻与术后并发症发生率降低有关。
评估术前体重减轻是否也与术后随时间推移体重减轻改善有关,以及这是否取决于术前体重指数(BMI)。
来自瑞典减肥手术国家登记处的数据。
在2008年1月1日至2011年11月30日接受初次胃旁路手术的20564例患者中,分析了9570例术前体重减轻和术后2年体重减轻数据完整的患者。
术前体重减轻的第25、50和75百分位数分别为0%、4.5%和8.6%。将术前体重减轻处于第50百分位数的患者与处于第25百分位数的患者进行比较时,术后1年和2年的总体重减轻分别高出5.0%和5.3%(P<0.001)。术前体重减轻处于第75百分位数的患者相应的值分别为11.8%和10.1%(P<0.001)。对于术前BMI处于第75百分位数(>45.7 kg/m²)的患者,这种效果更为明显。因此,在这组患者中且在术前体重减轻的第75百分位数范围内,与术前体重减轻处于第25百分位数的患者相比,1年和2年后的总体重减轻分别高出15.2%和13.6%。
在这个瑞典国家减肥登记数据集里,胃旁路手术前的体重减轻与术后持续改善的体重减轻有关。此外,术前和术后体重减轻的程度之间存在关联,且在高BMI患者中这种关联更强。