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Chromosomal sites for Marek's disease virus DNA in two chicken lymphoblastoid cell lines MDCC-MSB1 and MDCC-RP1.

作者信息

Hirai K, Maotani K, Ikuta K, Yasue H, Ishibashi M, Kato S

出版信息

Virology. 1986 Jul 15;152(1):256-61. doi: 10.1016/0042-6822(86)90390-9.

Abstract

In situ hybridization of viral DNA fragments to metaphase chromosomes of two chicken T-lymphoblastoid cell lines (MDCC) demonstrated that Marek's disease virus DNA was located in the short arm of chromosome 2 of MDCC-MSB1 and MDCC-RP1 cells and in the short arm of chromosome 4 of MDCC-MSB1 cells. The MDV DNA sequences in these chromosomes are not in the vicinity of oncogenes or integrated retroviruses that have been previously identified in chicken chromosomes.

摘要

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