Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 43000, China.
Department of Urology, Zhengzhou First People's Hospital, Zhengzhou, 450000, China.
Curr Med Sci. 2018 Aug;38(4):597-601. doi: 10.1007/s11596-018-1919-9. Epub 2018 Aug 20.
This prospective study was conducted to compare risk factors and pregnancy outcomes between women with complete placenta previa and those with incomplete placenta previa diagnosed in mid-pregnancy. The study was carried out from April 2014 to December 2015, during which 70 patients with complete previa and 113 with incomplete previa between 20 weeks and 25 weeks of gestation were included. Maternal demographics and pregnancy outcomes were compared between the two groups. Comparisons between categorical variables were tested by chi-squared test and those between continuous variables by Student t test. Resolution of previa occurred in 87.43% of the studied women. The mean gestational age at resolution was 32.1±4.4 weeks. Incidence of maternal age ≥35 years and incidence of prior uterine operation ≥3 were high in women with complete previa (28.6% vs 8.8%, P=0.003; 28.6% vs. 8.8%, P=0.003). Resolution of previa occurred less often in complete previa group (74.3% vs. 95.6%, P=0.001). Women with complete previa admitted earlier (37.3±2.0 weeks 38.1±1.4 weeks, P=0.011) and delivered earlier (37.7±1.2 weeks vs. 38.3±1.4 weeks, P=0.025). Maternal age ≥35 years and prior uterine operation ≥3 increase the risk of complete previa in mid-pregnancy. Placenta previa is more likely to persist in women with complete previa than those with incomplete previa diagnosed in midpregnancy. What is more, women with complete previa in mid-pregnancy delivers earlier.
本前瞻性研究旨在比较中孕期完全性前置胎盘和不完全性前置胎盘患者的危险因素和妊娠结局。该研究于 2014 年 4 月至 2015 年 12 月进行，共纳入 70 例完全性前置胎盘和 113 例 20-25 周妊娠的不完全性前置胎盘患者。比较两组患者的母体特征和妊娠结局。分类变量比较采用卡方检验，连续变量比较采用 t 检验。研究中 87.43%的患者胎盘前置得到缓解。胎盘前置缓解的平均孕龄为 32.1±4.4 周。完全性前置胎盘患者中年龄≥35 岁和既往子宫手术≥3 次的发生率较高（28.6%比 8.8%，P=0.003；28.6%比 8.8%，P=0.003）。完全性前置胎盘患者胎盘前置缓解的发生率较低（74.3%比 95.6%，P=0.001）。完全性前置胎盘患者入院时间较早（37.3±2.0 周比 38.1±1.4 周，P=0.011），分娩时间也较早（37.7±1.2 周比 38.3±1.4 周，P=0.025）。年龄≥35 岁和既往子宫手术≥3 次增加中孕期完全性前置胎盘的风险。与中孕期诊断为不完全性前置胎盘的患者相比，完全性前置胎盘患者更有可能持续存在。此外，中孕期完全性前置胎盘患者分娩时间更早。
