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股骨近端防旋髓内钉联合经Watson-Jones入路刮除植骨治疗股骨近端良性病变

[Treatment of proximal femoral benign lesions by proximal femoral nail anti-rotation combined with curettage and bone graft through the Watson-Jones approach].

作者信息

Liu Hongyuan, Xiong Yan, Fang Xiang, Duan Hong

机构信息

Department of Orthopedics, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P.R.China.

Department of Orthopedics, West China Hospital, Sichuan University, Chengdu Sichuan, 610041,

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2018 Jul 15;32(7):893-898. doi: 10.7507/1002-1892.201801128.

Abstract

OBJECTIVE

To evaluate the feasibility and effectiveness of proximal femoral nail anti-rotation (PFNA) combined with curettage and bone graft through Watson-Jones approach in the treatment of proximal femur benign tumors and tumor like lesions.

METHODS

The clinical data of 38 patients with benign tumors and tumor like lesions in the proximal femur who were treated through the Watson-Jones approach with PFNA combined with curettage and bone graft between January 2008 and January 2015 were retrospective analysed. There were 24 males and 14 females with an average age of 28 years (range, 15-57 years). Pathological types included 20 cases of fibrous dysplasia, 7 cases of bone cyst, 5 cases of aneurysmal bone cyst, 3 cases of giant cell tumor of bone, 2 cases of enchondroma, and 1 case of non-ossifying fibroma. Before operation, hip pain occurred in 19 patients, pathological fracture occurred in 12 patients, limb shortening and coxa varus deformity was found in 4 patients, and 3 patients received surgery for the local recurrence. The operation time, intraoperative blood loss, and full-weight bearing time after operation were recorded. Patients were followed up to observe union of bone graft and the position of internal fixator on X-ray films and CT images. Visual analogue scale (VAS) score was used to evaluate the level of pain. The Musculoskeletal Tumor Society (MSTS93) score was used to evaluate lower limb function. Harris hip score was used to evaluate hip joint function.

RESULTS

The operation time was 130-280 minutes (mean, 182 minutes) and the intraoperative blood loss was 300-1 500 mL (mean, 764 mL). After operation, 3 cases of fat liquefaction of incision healed successfully by carefully dressing, and the rest incisions healed by first intention. All patients started partially weight-bearing exercise at 2-4 weeks after operation. The total weight-bearing time was 3-6 months (mean, 4.2 months). All the patients were followed up 24-108 months (median, 60 months). Imaging examination showed that the bone graft fused and the fusion time was 8-18 months (mean, 11.4 months). During the follow-up period, there was no complication such as pathological fracture, femoral head ischemic necrosis, hip joint dislocation, internal fixation loosening and fracture, and no tumor recurrence or distant metastasis occurred. At last follow-up, the VAS score, MSTS93 score, and Harris score were significantly improved when compared with preoperative ones ( <0.05).

CONCLUSION

The treatment of proximal femoral benign lesions by PFNA combined with curettage and bone graft through the Watson-Jones approach is safe and effective, with advantages of better mechanical stability, less residual tumor, and less postoperative complications.

摘要

目的

评估股骨近端防旋髓内钉(PFNA)联合经Watson-Jones入路刮除植骨术治疗股骨近端良性肿瘤及瘤样病变的可行性和有效性。

方法

回顾性分析2008年1月至2015年1月间采用Watson-Jones入路行PFNA联合刮除植骨术治疗的38例股骨近端良性肿瘤及瘤样病变患者的临床资料。其中男性24例,女性14例,平均年龄28岁(15 - 57岁)。病理类型包括纤维发育不良20例、骨囊肿7例、动脉瘤样骨囊肿5例、骨巨细胞瘤3例、内生软骨瘤2例、非骨化性纤维瘤1例。术前,19例患者出现髋关节疼痛,12例患者发生病理性骨折,4例患者存在肢体短缩及髋内翻畸形,3例患者因局部复发接受手术。记录手术时间、术中出血量及术后完全负重时间。对患者进行随访,观察X线片及CT图像上植骨融合情况及内固定位置。采用视觉模拟评分法(VAS)评估疼痛程度。采用肌肉骨骼肿瘤学会(MSTS93)评分评估下肢功能。采用Harris髋关节评分评估髋关节功能。

结果

手术时间为130 - 280分钟(平均182分钟),术中出血量为300 - 1500毫升(平均764毫升)。术后,3例切口脂肪液化经精心换药后愈合,其余切口一期愈合。所有患者术后2 - 4周开始部分负重锻炼。完全负重时间为3 - 6个月(平均4.2个月)。所有患者均获随访24 - 108个月(中位随访时间60个月)。影像学检查显示植骨融合,融合时间为8 - 18个月(平均11.4个月)。随访期间,未出现病理性骨折、股骨头缺血坏死、髋关节脱位、内固定松动及断裂等并发症,无肿瘤复发及远处转移发生。末次随访时,VAS评分、MSTS93评分及Harris评分与术前相比均显著改善(<0.0^5)。

结论

PFNA联合经Watson-Jones入路刮除植骨术治疗股骨近端良性病变安全有效,具有机械稳定性好、肿瘤残留少、术后并发症少等优点。

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