Bertram Christof A, Müller Kerstin, Halter Lesley, Nastarowitz-Bien Christiane, Schink Anne-Katrin, Lübke-Becker Antina, von Czapiewski Ellen, Klopfleisch Robert
1 Institute of Veterinary Pathology, Freie Universität Berlin, Berlin, Germany.
2 Small Animal Clinic, Freie Universität Berlin, Berlin, Germany.
Vet Pathol. 2019 Jan;56(1):152-156. doi: 10.1177/0300985818790789. Epub 2018 Aug 21.
Acquired outpouches of the intestinal tract are referred to as pseudodiverticula or false pulsion diverticula. In contrast to true diverticula, in which the wall contains all layers of the intestinal tract, the wall of pseudodiverticula lacks the tunica muscularis. Smooth muscle hypertrophy of the small intestine is commonly considered a cause of pseudodiverticulosis in animals due to increased intraluminal pressure. This study reports pseudodiverticula associated with idiopathic smooth muscle hypertrophy of the small intestine in lagomorphs. Four domestic rabbits had single or multiple (up to 200) pseudodiverticula of various size in the small intestine. In all cases the tunica muscularis was diffusely thickened, significantly exceeding reference thickness of 14 rabbits (mean, 112.3 µm; range, 26.3-389.0 µm). Clinical signs were considered to be caused by severe necrosis and inflammation of the wall of large pseudodiverticula, leading to perforation with subsequent peritonitis and mesenteric and omental abscess formation in 2 cases.
肠道后天性憩室被称为假性憩室或假性压力性憩室。与真性憩室不同，真性憩室壁包含肠道的所有层，而假性憩室壁缺乏肌层。由于管腔内压力增加，小肠平滑肌肥大通常被认为是动物假性憩室病的一个原因。本研究报告了兔科动物中与特发性小肠平滑肌肥大相关的假性憩室。四只家兔在小肠中有单个或多个（多达200个）大小各异的假性憩室。在所有病例中，肌层均弥漫性增厚，显著超过14只对照兔的参考厚度（平均112.3 µm；范围26.3 - 389.0 µm）。临床症状被认为是由大的假性憩室壁严重坏死和炎症引起的，导致2例出现穿孔，随后发生腹膜炎以及肠系膜和网膜脓肿形成。
