Jang Hyomi, Kim Sang-Woo, Lee Joon Woo, Kim Munso, Jung Dong-In
VIP Animal Medical Center (Cheongdam), Seoul 06068, Republic of Korea.
College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Animals (Basel). 2025 Apr 23;15(9):1199. doi: 10.3390/ani15091199.
A 3-year-old intact female French Bulldog presented with chronic diarrhea, intermittent vomiting, hyporexia, and weight loss over seven weeks. The blood test results were unremarkable, except for mild hypocholesterolemia. Abdominal ultrasonography revealed intestinal wall thickening, particularly in the muscular layer, with focal loss of wall layering in the distal ileum near the ileocecal junction. Capsule endoscopy revealed mild-to-moderate mucosal irregularities and changes in the ileum, with a reduced luminal diameter caused by irregularly protruding walls, leading to the partial obstruction of the distal ileum. To remove the obstructed segment, surgical resection and anastomosis were performed from the distal ileum to the ileocecal junction, including the ileocolic valve region. Histopathological examination confirmed intestinal smooth muscle hyperplasia with mild infiltration of macrophages, neutrophils, and lymphocytes. As the underlying cause could not be identified, the condition was classified as an idiopathic condition. Postoperatively, long-term management of the clinical symptoms was implemented, including antibiotics, anti-inflammatory medications, and dietary modifications (the elimination of table foods). Over a one-year follow-up period, ultrasonography revealed mild recurrent inflammation and muscular hyperplasia; however, the clinical signs resolved, except for occasional episodes of diarrhea.
一只3岁未绝育的雌性法国斗牛犬出现慢性腹泻、间歇性呕吐、食欲减退和体重减轻达7周之久。血液检测结果无明显异常，仅轻度低胆固醇血症。腹部超声检查显示肠壁增厚，尤其是肌层，在回盲部附近的回肠远端壁层有局灶性缺失。胶囊内镜检查显示回肠有轻度至中度黏膜不规则及改变，因壁不规则突出导致管腔直径减小，引起回肠远端部分梗阻。为切除梗阻段，从回肠远端至回盲部进行了手术切除和吻合，包括回结肠瓣区域。组织病理学检查证实肠平滑肌增生，伴有巨噬细胞、中性粒细胞和淋巴细胞轻度浸润。由于无法确定潜在病因，该病症被归类为特发性病症。术后，实施了对临床症状的长期管理，包括使用抗生素、抗炎药物和调整饮食（去除餐桌食物）。在为期一年的随访期内，超声检查显示有轻度复发性炎症和肌肉增生；然而，除偶尔出现腹泻外，临床症状已缓解。
