中耳积液中胶原酶活性的生化特性

Biochemical characterization of collagenase activity from middle ear effusions.

作者信息

Granström G, Holmquist J, Jarlstedt J, Renvall U

出版信息

Auris Nasus Larynx. 1985;12 Suppl 1:S141-4. doi: 10.1016/s0385-8146(85)80128-0.

Abstract

Collagenolytic enzyme activity has been demonstrated in middle ear effusions from patients suffering from otitis media with effusion. Collagenase activity was characterized using different biochemical techniques. The enzyme was found to have a higher specific activity in mucoid effusions and had characteristics similar to granulocyte derived collagenase from human leucocytes.

摘要

在患有渗出性中耳炎患者的中耳积液中已证实存在胶原酶活性。使用不同的生化技术对胶原酶活性进行了表征。发现该酶在黏液样积液中具有较高的比活性，并且具有与源自人白细胞的粒细胞胶原酶相似的特性。