通过淋巴结生发中心超微结构检查诊断人类嗜T淋巴细胞病毒III型感染——病例报告
Diagnosis of HTLV-III infection by ultrastructural examination of germinal centers in lymph node--a case report.
作者信息
Warner T F, Crass B, Gabel C, Maki D, Hafez G R, Golubjatnikov R
出版信息
AIDS Res. 1986 Feb;2(1):43-50. doi: 10.1089/aid.1.1986.2.43.
PMID:3013218
Abstract
Serum from a patient suspected of having AIDS showed positive ELISA tests but the diagnostic p 41 band was absent and the p 24 band was barely discernible on a Western blot. Before another Western blot was performed lentivirions were detected between dendritic reticulum cells in a lymph node biopsy. It is suggested that samples of biopsies of lymph nodes from patients with or at risk for AIDS should be embedded in resin for future ultrastructural study if indicated.
摘要
一名疑似患有艾滋病的患者的血清ELISA检测呈阳性，但在蛋白质印迹法中诊断性的p41条带缺失，p24条带几乎难以辨认。在进行另一次蛋白质印迹法检测之前，在淋巴结活检的树突状网状细胞之间检测到慢病毒颗粒。建议如果有指征，艾滋病患者或有艾滋病风险患者的淋巴结活检样本应包埋在树脂中以备将来进行超微结构研究。
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