Clinical Professor of Internal Medicine, Allergy/Immunology Division, University of Texas Southwestern Medical School, private practice, Dallas, TX. Email:
Am J Manag Care. 2018 Aug;24(14 Suppl):S299-S307.
Hereditary angioedema (HAE) is a rare genetic disease defined by recurrent attacks of edema, causing a substantial burden for patients, with morbidity, mortality, and reduced quality of life. This burden is increased by delayed diagnosis, inappropriate treatment, and suboptimal follow-up and patient education. Several novel therapeutics have recently been approved or are currently under evaluation for prevention of HAE attacks.
遗传性血管性水肿（HAE）是一种罕见的遗传性疾病，其特征为反复发作的水肿，给患者带来了巨大的负担，导致发病率、死亡率和生活质量下降。诊断延迟、治疗不当以及随访和患者教育不佳进一步加重了这种负担。最近已经批准了几种新型治疗药物，或者正在评估其用于预防 HAE 发作。
