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深脑刺激的固定寿命或可充电电池:患者更喜欢哪种?

Fixed-Life or Rechargeable Battery for Deep Brain Stimulation: Which Do Patients Prefer?

机构信息

Department of Neurosurgery, King's College Hospital, Denmark Hill, London, UK.

出版信息

Neuromodulation. 2019 Jun;22(4):489-492. doi: 10.1111/ner.12810. Epub 2018 Aug 22.

DOI:10.1111/ner.12810
PMID:30133071
Abstract

BACKGROUND

Deep brain stimulation (DBS) is increasingly used to treat a wide variety of neurological and psychiatric disorders. Implantable pulse generators (implantable pulse generators/batteries) for DBS were originally only available as a nonrechargeable option. However, there is now a choice between fixed-life and rechargeable batteries, with each having their own advantages and disadvantages. The extent of patient involvement in the choice of battery and the factors that matter to them have not been well studied.

METHODS

Thirty consecutive adult patients with movement disorders attending a pre-DBS clinic were offered a choice of fixed-life or rechargeable battery and completed a questionnaire after the consultation on which factors influenced their decision.

RESULTS

Nineteen patients (63%) chose the fixed-life battery and 11 patients (37%) chose the rechargeable battery. There were no significant differences in age, sex, underlying disease, disease duration or Unified Parkinson's Disease Rating Scale (UPDRS) (part 3) score (for patients with Parkinson disease) between those who chose the fixed-life vs. rechargeable battery. Most patients were not concerned about the size of the battery. Equal numbers were concerned about surgery to replace the battery, and less than half were concerned about the need to recharge the battery. More than half of patients felt that an acceptable charging frequency was monthly or yearly, and all patients felt that an acceptable charging duration was less than 1 hour, with half of all patients choosing less than 30 min. The main reasons cited for choosing the fixed-life battery were convenience and concern about forgetting to recharge the battery. The main reason for choosing the rechargeable battery was the avoidance of further surgery.

DISCUSSION

Most patients in this adult cohort with movement disorders chose the fixed-life battery. The better lifestyle associated with a fixed-life battery is a major factor influencing their choice. Rechargeable batteries may be more acceptable if the recharging process is improved, more convenient, and discreet.

CONFLICT OF INTEREST

The authors' institution has received educational grants from Medtronic, Abbott, and Boston Scientific companies.

摘要

背景

深部脑刺激(DBS)越来越多地用于治疗各种神经和精神疾病。DBS 的植入式脉冲发生器(植入式脉冲发生器/电池)最初仅提供不可充电选项。然而,现在可以在固定寿命和可充电电池之间进行选择,每种电池都有其自身的优点和缺点。患者在电池选择中所涉及的程度以及对他们重要的因素尚未得到充分研究。

方法

连续 30 位患有运动障碍的成年患者在接受 DBS 前诊所就诊时,被提供了固定寿命或可充电电池的选择,并在咨询后完成了一份问卷,说明影响他们决策的因素。

结果

19 名患者(63%)选择了固定寿命电池,11 名患者(37%)选择了可充电电池。在选择固定寿命与可充电电池的患者之间,年龄、性别、基础疾病、疾病持续时间或统一帕金森病评定量表(UPDRS)(第 3 部分)评分(帕金森病患者)无显著差异。大多数患者并不关心电池的大小。同样数量的患者担心要进行电池更换手术,不到一半的患者担心需要给电池充电。超过一半的患者认为每月或每年的充电频率可以接受,所有患者都认为充电时间少于 1 小时是可以接受的,其中一半的患者选择少于 30 分钟。选择固定寿命电池的主要原因是方便和担心忘记给电池充电。选择可充电电池的主要原因是避免进一步手术。

讨论

在这个患有运动障碍的成年患者队列中,大多数患者选择了固定寿命电池。与固定寿命电池相关的更好的生活方式是影响他们选择的主要因素。如果充电过程得到改善、更方便且更隐蔽,可充电电池可能会更受欢迎。

利益冲突

作者所在机构已从美敦力、雅培和波士顿科学公司获得教育赠款。

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