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大鼠的前庭丘脑连接:使用小麦胚凝集素-辣根过氧化物酶的形态学分析。

The vestibulothalamic connections in the rat: a morphological analysis using wheat germ agglutinin-horseradish peroxidase.

作者信息

Nagata S

出版信息

Brain Res. 1986 Jun 18;376(1):57-70. doi: 10.1016/0006-8993(86)90899-1.

DOI:10.1016/0006-8993(86)90899-1
PMID:3013377
Abstract

The vestibulothalamic connections were studied in the rat using wheat germ agglutinin-horseradish peroxidase (WGA-HRP). The distributions of anterograde labelling of fibers and terminals in the brainstem and the thalamus were analyzed by injecting WGA-HRP into the superior (SVN) and lateral (LVN) vestibular nuclei, and the medial (MVN) and inferior (IVN) vestibular nuclei. The distributions of retrograde labelling of cells were analyzed in the vestibular nuclear complex by injecting WGA-HRP into the thalamus centered in the central lateral nucleus (CL), ventral posterolateral nucleus (VPL), and rostral part of the dorsal medial geniculate nucleus (rMGd). The vestibular projection to the CL via the medial longitudinal fasciculus (MLF) and the ascending tract of Deiters (ATD) originates mainly in the contralateral MVN and ipsilateral SVN. The vestibular projections to the VPL and the ventral lateral nucleus (VL) via MLF, ATD and superior cerebellar peduncle (SCP) originate mainly in the MVN and SVN, bilaterally. The projection to the rMGd via the lateral lemniscus-inferior collicular brachium, and MLF (and SCP) originates in the contralateral IVN.

摘要

利用小麦胚凝集素-辣根过氧化物酶(WGA-HRP)对大鼠的前庭丘脑连接进行了研究。通过将WGA-HRP注入上(SVN)、外侧(LVN)前庭核以及内侧(MVN)、下(IVN)前庭核,分析了脑干和丘脑中纤维和终末顺行标记的分布。通过将WGA-HRP注入以中央外侧核(CL)、腹后外侧核(VPL)和背内侧膝状体核头端部分(rMGd)为中心的丘脑,分析了前庭核复合体中细胞逆行标记的分布。经内侧纵束(MLF)和戴特斯升束(ATD)至CL的前庭投射主要起源于对侧MVN和同侧SVN。经MLF、ATD和上小脑脚(SCP)至VPL和腹外侧核(VL)的前庭投射主要双侧起源于MVN和SVN。经外侧丘系-下丘臂和MLF(及SCP)至rMGd的投射起源于对侧IVN。

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