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基于机器学习技术的超窄带探头近场乳腺肿瘤检测。

Near Field Breast Tumor Detection Using Ultra-Narrow Band Probe with Machine Learning Techniques.

机构信息

Department of Electrical Engineering, Hadhramout University, Al Mukalla, Yemen.

Department of Electrical and Computer Engineering, Waterloo, N2L3G1, Canada.

出版信息

Sci Rep. 2018 Aug 22;8(1):12607. doi: 10.1038/s41598-018-31046-9.

DOI:10.1038/s41598-018-31046-9
PMID:30135484
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6105675/
Abstract

In this work, we propose a near-field microwave sensing modality that uses a single probe combined with a classification algorithm to help in detecting the presence of tumors in the human female breast. The concept employs a near-field resonant probe with an ultra-narrow frequency response. The resonant probe is highly sensitive to the changes in the electromagnetic properties of the breast tissues such that the presence of the tumor is gauged by determining the changes in the magnitude and phase response of the sensor's reflection coefficient. A key feature of our proposed detection concept is the simultaneous sensing of tissue property changes to the two female breasts since the right and left healthy breasts are morphologically and materially identical. Once the probe response is recorded for both breasts, the Principle Component Analysis (PCA) method is employed to emphasize the difference in the probe responses. For validation of the concept, tumors embedded in a realistic breast phantoms were simulated. To provide additional confidence in the detection modality introduced here, experimental results of three different sizes of metallic spheres, mimicking tumors, inserted inside chicken and beef meat were detected using an electrically-small probe operating at 200 MHz. The results obtained from the numerical tests and experiments strongly suggest that the detection modality presented here might lead to an inexpensive and portable early and regular screening for breast tumor.

摘要

在这项工作中,我们提出了一种近场微波传感模式,该模式使用单个探头结合分类算法来帮助检测女性乳房中肿瘤的存在。该概念采用具有超窄频率响应的近场谐振探头。谐振探头对乳房组织的电磁特性变化非常敏感,因此通过确定传感器反射系数的幅度和相位响应的变化来测量肿瘤的存在。我们提出的检测概念的一个关键特征是同时感测两个女性乳房的组织特性变化,因为右侧和左侧健康乳房在形态和材料上是相同的。一旦记录了探头对两个乳房的响应,就采用主成分分析 (PCA) 方法来强调探头响应的差异。为了验证该概念,在现实的乳房仿体中模拟了嵌入的肿瘤。为了为这里介绍的检测模式提供更多信心,使用工作在 200MHz 的电小探头检测了嵌入鸡肉和牛肉中的三个不同尺寸的金属球,模拟肿瘤,得到了实验结果。数值测试和实验结果强烈表明,这里提出的检测模式可能会导致用于早期和定期筛查乳房肿瘤的廉价、便携式方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef2d/6105675/25422763f2c5/41598_2018_31046_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef2d/6105675/94ecba700f0e/41598_2018_31046_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef2d/6105675/5d96f91c67d4/41598_2018_31046_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef2d/6105675/25422763f2c5/41598_2018_31046_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef2d/6105675/94ecba700f0e/41598_2018_31046_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef2d/6105675/5d96f91c67d4/41598_2018_31046_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef2d/6105675/25422763f2c5/41598_2018_31046_Fig3_HTML.jpg

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