Mazurenko N N, Fedorov S N, Bogovskiĭ B P, Kniazev P G, Seĭts I F
Eksp Onkol. 1986;8(3):18-21.
The structural proteins and the oncogene product of the avian sarcoma virus (ASV) D6 were analyzed by the radioimmunoprecipitation. ADV D6 was obtained from the chemically induced tumour. ASV D6 contains all the structural proteins found in RSV, but some of them (p19, gp 85) differ from those of RSV. The product of ASV D6 oncogene is pp65src. The protein kinase activity of this src protein is identical to that of wt pp60src. The nature of some other proteins, which can be phosphorylated in this reaction, is discussed.
通过放射免疫沉淀法对禽肉瘤病毒（ASV）D6的结构蛋白和癌基因产物进行了分析。ASV D6是从化学诱导的肿瘤中获得的。ASV D6含有劳斯肉瘤病毒（RSV）中发现的所有结构蛋白，但其中一些蛋白（p19、gp 85）与RSV的不同。ASV D6癌基因的产物是pp65src。这种src蛋白的蛋白激酶活性与野生型pp60src的相同。还讨论了在该反应中可被磷酸化的其他一些蛋白的性质。
