眼眶假瘤的放射治疗：佛罗里达大学的经验
Radiotherapy for Orbital Pseudotumor: The University of Florida Experience.
作者信息
Mokhtech Meriem, Nurkic Sommer, Morris Christopher G, Mendenhall Nancy P, Mendenhall William M
机构信息
a Department of Radiation Oncology , University of Florida College of Medicine , Gainesville , FL , USA.
出版信息
Cancer Invest. 2018;36(6):330-337. doi: 10.1080/07357907.2018.1489550. Epub 2018 Aug 23.
BACKGROUND
To evaluate outcomes after definitive radiotherapy for orbital pseudotumor.
METHODS
We reviewed adult patients treated between 1971 and 2012.
RESULTS
20 patients with 8.0-year median follow-up were analyzed. Symptoms improved in 75% of patients: 40% showed a complete response, 35% partial response, and 20% had stable disease. The disease progressed in 1 and recurred in 8 patients. Local control rates were 63% and 53% at 5 and 10 years, respectively. The most common toxicities were cataracts (10%) and dry eye (10%).
CONCLUSIONS
Radiotherapy for orbital pseudotumor is well-tolerated and results in long-term control in most patients, with local control in over half.
背景
评估眼眶假瘤根治性放疗后的疗效。
方法
我们回顾了1971年至2012年间接受治疗的成年患者。
结果
分析了20例患者，中位随访时间为8.0年。75%的患者症状改善：40%完全缓解，35%部分缓解，20%病情稳定。1例疾病进展，8例复发。5年和10年的局部控制率分别为63%和53%。最常见的毒性反应是白内障（10%）和干眼（10%）。
结论
眼眶假瘤放疗耐受性良好，大多数患者可获得长期控制，超过半数患者可实现局部控制。
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