Visceral Surgery Department, Geneva University Hospital, Genève, Switzerland.
Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany.
Ann N Y Acad Sci. 2018 Dec;1434(1):132-138. doi: 10.1111/nyas.13954. Epub 2018 Aug 23.
Management of gastroesophageal junction (GEJ) adenocarcinoma is a controversial topic. The rising incidence of this cancer requires a clear consensus to ensure proper management. Application of oncological principles for tumors of the esophagus or stomach is not possible because of comparative differences in the biology of GEJ adenocarcinoma, leading to different therapeutic options. Staging work-up with endoscopy, endosonography, and PET is essential to inform the choice of neoadjuvant treatment and surgical approach to GEJ adenocarcinoma. Surgery remains the only curative treatment and should be undertaken in specialized centers.
胃食管结合部（GEJ）腺癌的治疗是一个有争议的话题。这种癌症的发病率不断上升，需要达成明确的共识，以确保进行适当的治疗。由于 GEJ 腺癌的生物学特性存在差异，不能简单地套用食管或胃肿瘤的肿瘤学原则，这导致了不同的治疗选择。通过内镜、超声内镜和 PET 进行分期检查对于告知新辅助治疗和 GEJ 腺癌手术方法的选择至关重要。手术仍然是唯一的治愈性治疗方法，应在专业中心进行。
