在皮层折叠的力学和遗传学之间架起桥梁：细胞外基质作为主要驱动力。
Bridging the Gap between Mechanics and Genetics in Cortical Folding: ECM as a Major Driving Force.
机构信息
Univ Lyon, Université Claude Bernard Lyon 1, Inserm, Stem Cell and Brain Research Institute U1208, 69500 Bron, France.
Univ Lyon, Université Claude Bernard Lyon 1, Inserm, Stem Cell and Brain Research Institute U1208, 69500 Bron, France; Institute of Neuroscience, State Key Laboratory of Neuroscience, Chinese Academy of Sciences (CAS) Key Laboratory of Primate Neurobiology, CAS, Shanghai 200031, China.
出版信息
Neuron. 2018 Aug 22;99(4):625-627. doi: 10.1016/j.neuron.2018.08.012.
Folding of the cerebral cortex results from interrelated biological and mechanical processes that are incompletely understood. In this issue, Long et al. identify the key roles of HAPLN1, lumican, collagen I, and HA in relationship with changes in tissue stiffness.
大脑皮层的折叠是由相互关联的生物学和力学过程引起的，但这些过程尚未完全被理解。在本期杂志中，Long 等人确定了 HAPLN1、lumican、胶原 I 和透明质酸在与组织硬度变化相关的关系中的关键作用。
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