Institut de Radioprotection et de Sûreté Nucléaire (IRSN), Service de Recherche en Dosimétrie, Laboratoire de Dosimétrie des Rayonnements Ionisants, Fontenay-aux-Roses, France.
Institut de Radioprotection et de Sûreté Nucléaire (IRSN), Service de Recherche en Dosimétrie, Laboratoire de Dosimétrie des Rayonnements Ionisants, Fontenay-aux-Roses, France.
Phys Med. 2018 Aug;52:154-164. doi: 10.1016/j.ejmp.2018.07.002. Epub 2018 Aug 4.
This study aims at characterising the properties of TruView™ and ClearView™ two new gel dosimeters (Modus Medical Devices Inc.) and at studying the feasibility of relative dosimetry using these dosimeters and the Vista™ Optical CT scanner to accurately evaluate dose.
In this work, we investigated key dosimetric aspects (dose response, energy and dose rate dependence) and stability of these radiochromic gels initiated in preliminary works (Huet et al., 2017; Colnot et al., 2017) using spectrophotometric measurements. Moreover, by mean of optical CT scanning (Vista™), their performances to measure relative depth dose (PDD) and cross profiles were analysed.
TruView™ and ClearView™ present a linear dose response up to 20 Gy and up to 80 Gy respectively, independent of both photon beam energy (4-18 MV) and dose rate (up to 9.9 Gy/min) (Huet et al., 2017; Colnot et al., 2017). ClearView™ response proves to be stable for a week post-irradiation and uniform within the batch whereas TruView™ presents an unstable but uniform response. Optical CT scanning generates errors due to stray light that need to be corrected in order to use these gels; ClearView™ scanning particularly requires important precautions. After corrections, those gels used in combination with the Vista™ scanner show promising spatial and dosimetric precision (dose difference <5%). Finally, TruView™ is reusable and presents excellent reproducible response (maximum 3% difference) and the ClearView™ dosimeter presents good spatial stability (0.5% difference after 6 days).
This study provides important knowledge about two gel dosimeters presenting interesting dosimetric properties. A study is ongoing to benchmark those promising candidates for clinical dose verification.
本研究旨在描述 TruView™ 和 ClearView™ 两种新型凝胶剂量计(Modus Medical Devices Inc.)的特性,并研究使用这些剂量计和 Vista™ 光学 CT 扫描仪进行相对剂量测量的可行性,以准确评估剂量。
在这项工作中,我们使用分光光度法对初步研究(Huet 等人,2017 年;Colnot 等人,2017 年)中提出的关键剂量学方面(剂量响应、能量和剂量率依赖性)和这些放射色凝胶的稳定性进行了研究。此外,还通过光学 CT 扫描(Vista™)分析了它们测量相对深度剂量(PDD)和横截面的性能。
TruView™ 和 ClearView™ 的剂量响应均呈线性,在 4-18 MV 光子束能量和高达 9.9 Gy/min 的剂量率范围内,分别可达 20 Gy 和 80 Gy(Huet 等人,2017 年;Colnot 等人,2017 年)。ClearView™ 的响应在辐照后一周内稳定且均匀,而 TruView™ 的响应则不稳定但均匀。光学 CT 扫描会产生杂散光误差,需要进行校正才能使用这些凝胶;ClearView™ 扫描特别需要重要的预防措施。校正后,这些与 Vista™ 扫描仪结合使用的凝胶显示出有前途的空间和剂量精度(剂量差异<5%)。最后,TruView™ 可重复使用,具有出色的可重复性响应(最大 3%的差异),而 ClearView™ 剂量计具有良好的空间稳定性(6 天后差异为 0.5%)。
本研究提供了关于两种具有有趣剂量学特性的凝胶剂量计的重要知识。目前正在进行一项研究,以基准测试这些有前途的候选者用于临床剂量验证。