Fukumoto Kana, Manabe Yasuhiro, Fujiwara Shunya, Omote Yoshio, Narai Hisashi, Yamada Haruto, Saito Takashi, Abe Koji
Department of Neurology, National Hospital Organization Okayama Medical Center, Okayama, Japan.
Department of Infectious Diseases, National Hospital Organization Okayama Medical Center, Okayama, Japan.
Case Rep Neurol. 2018 Jul 18;10(2):177-180. doi: 10.1159/000490695. eCollection 2018 May-Aug.
We report a rare case of meningitis due to a combination of and . An 80-year-old female had a 4-year history of type II diabetes mellitus (DM) and an 11-year history of rheumatoid arthritis, which was treated with prednisolone, tacrolimus, and methotrexate. One month after the removal of a dental implant, she complained of a disturbance of consciousness and suffered a convulsion. A cerebrospinal fluid culture was found to be positive for both and . After 14 days of antibiotic treatment with 4 g/day ceftriaxone, her stiff neck, somnolence, and laboratory data greatly improved, and she was successfully discharged at 27 days after admission. Although both and are generally considered to be benign bacteria, they can cause meningitis in patients with the following risk factors: older age, on immunosuppressive treatment, DM, or dental treatment.
我们报告了一例由[两种细菌名称未给出]组合导致的罕见脑膜炎病例。一名80岁女性有2型糖尿病（DM）4年病史和类风湿关节炎11年病史，曾用泼尼松龙、他克莫司和甲氨蝶呤治疗。在拔除一颗牙种植体一个月后，她主诉意识障碍并发生惊厥。脑脊液培养发现[两种细菌名称未给出]均呈阳性。在用每天4克头孢曲松进行14天抗生素治疗后，她的颈部僵硬、嗜睡及实验室检查数据有很大改善，入院27天后成功出院。尽管[两种细菌名称未给出]通常被认为是良性细菌，但它们可在有以下危险因素的患者中引起脑膜炎：年龄较大、接受免疫抑制治疗、患有DM或接受牙科治疗。
