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首例由凝结芽胞杆菌引起的脑膜炎的人感染病例报告。

First reported human case of meningitis by Staphylococcus condimenti.

机构信息

S.C.D.U. Medicina Interna I, A.O.U. Maggiore Della Carità, Università del Piemonte Orientale, via Mazzini 18, 28100, Novara, Italy.

出版信息

Infection. 2019 Aug;47(4):651-653. doi: 10.1007/s15010-018-01266-2. Epub 2019 Feb 7.

DOI:10.1007/s15010-018-01266-2
PMID:30734247
Abstract

Staphylococcus condimenti (S. condimenti) is a coagulase-negative bacterium, generally regarded as not pathogenic. Indeed, S. condimenti owes its name to having been isolated from starter cultures of fermented sausage, as well as from fish and soy sauces. To the best of our knowledge, only two cases of human infection caused by this bacterium have been reported. Here, we present a case of meningitis by S. condimenti in a 65-year-old woman who was brought to hospital after having been found unconscious at home. At her arrival, she had a Glasgow coma scale = 3, fever, and hypoxic-normocapnic respiratory failure. Examination of her cerebrospinal fluid showed a slightly increased white blood cell count, normal glucose and protein concentrations. Paired cultures on blood and liquor samples yielded S. condimenti. Targeted antibiotic treatment with ceftriaxone led to a complete recovery. This unique case expands our knowledge on S. condimenti as a pathogenic bacterium.

摘要

凝结酶阴性葡萄球菌(S. condimenti)是一种凝固酶阴性细菌,通常被认为无致病性。事实上,S. condimenti 这个名称来源于它从发酵香肠的发酵剂中以及从鱼露和酱油中分离出来。据我们所知,这种细菌引起的人类感染仅有两例报道。在此,我们报告了一例由 S. condimenti 引起的脑膜炎,患者为一名 65 岁女性,在家中被发现意识不清后被送往医院。入院时,她的格拉斯哥昏迷量表评分为 3 分,伴有发热和低氧性低碳酸血症性呼吸衰竭。她的脑脊液检查显示白细胞计数略有增加,葡萄糖和蛋白质浓度正常。血液和脑脊液样本的配对培养均培养出 S. condimenti。采用头孢曲松进行靶向抗生素治疗后患者完全康复。这个独特的病例扩展了我们对 S. condimenti 作为一种致病性细菌的认识。

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本文引用的文献

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2
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3
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