Laboratory of Bioengineering, Department of Experimental Diagnostic and Specialty Medicine (DIMES), Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy.
Ophthalmology Unit, Department of Experimental Diagnostic and Specialty Medicine (DIMES), University of Bologna, S. Orsola-Malpighi Teaching Hospital, Bologna, Italy.
J Healthc Eng. 2018 Jul 22;2018:3271269. doi: 10.1155/2018/3271269. eCollection 2018.
Fusional vergence is a disjunctive movement of the eyes that is made in order to obtain single vision. The aim of the study was to provide a quantitative and objective approach for analyzing the fusional convergence response using eye tracking (ET) technology and automatic data analysis provided by the intuitive SacLab toolbox previously developed by our group. We evaluated the proposed approach in a population of 26 subjects with normal binocular vision, who were tested with base-out prisms (magnitudes 4Δ, 6Δ, and 10Δ) in order to elicit fusional convergence response. Eye movements were recorded using the Viewpoint ET and analyzed using SacLab. Parameters describing both the vergence and the version components of the fusional response (convergence duration, CD; peak convergence velocity, PCV; number of intrusive saccades, NS; and mean saccadic amplitude, MSA) were automatically calculated and provided to clinicians for an objective evaluation. Results showed that the number of subjects achieving fusional convergence decreased with prism magnitude. For subjects achieving fusion CD and PCV increased significantly ( < 0.05) when increasing the prism magnitude. For NS and MSA, there were no significant changes when passing to 6Δ, but a significant increase resulted when passing to 10Δ ( < 0.05). Noninvasive ET associated with the intuitive SacLab toolbox may represent a valid option to objectively characterize the fusional vergence response in clinical setting. The analysis may be extended to patients with vergence disorders.
融像性集合是一种眼睛的离散运动，目的是获得单一视觉。本研究的目的是提供一种使用眼动追踪（ET）技术和我们小组之前开发的直观 SacLab 工具箱提供的自动数据分析来分析融像性集合反应的定量和客观方法。我们在 26 名具有正常双眼视觉的受试者中评估了该方法，他们使用基底外向棱镜（4Δ、6Δ 和 10Δ）进行测试以引发融像性集合反应。使用 Viewpoint ET 记录眼动，并使用 SacLab 进行分析。描述集合反应的集合和版本分量的参数（集合持续时间 CD、集合峰值速度 PCV、侵入性眼跳的数量 NS 和平均眼跳幅度 MSA）自动计算并提供给临床医生进行客观评估。结果表明，随着棱镜幅度的增加，达到融像性集合的受试者数量减少。对于达到融合的受试者，CD 和 PCV 随着棱镜幅度的增加而显著增加（<0.05）。对于 NS 和 MSA，当增加到 6Δ 时没有显著变化，但当增加到 10Δ 时会显著增加（<0.05）。非侵入性 ET 与直观的 SacLab 工具箱相结合，可能是在临床环境中客观描述融像性集合反应的有效选择。分析可以扩展到集合障碍患者。
