Weerarathna Thilak Priyantha, Weerarathna Miyuru Kavinda, Senadheera Vidarsha, Meththananda Herath Herath Mudiyanselage, Liyanage Gayani
Faculty of Medicine, University of Ruhuna, Matara, Sri Lanka.
Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
J Nutr Metab. 2018 Jul 24;2018:3421476. doi: 10.1155/2018/3421476. eCollection 2018.
Influence of dietary and drug compliance of patients with diabetes on attainment of optimal metabolic (glucose and lipid) control remains underexplored in developing countries.
Self-reported dietary and drug compliance score of 0-10, glycosylated hemoglobin (HbA1c), and low-density lipoprotein (LDL) levels were obtained from patients with diabetes. HbA1c <7% and LDL <100 mg/dL were used to define optimal glucose and lipid control, respectively. Proportions achieving each and both optimal parameters were estimated. Regression analysis was used to study the association of age, gender, age of onset and the duration of diabetes, self-reported dietary, and drug compliance scores with achievement of both parameters.
Mean (SD) age and duration of diabetes of 207 patients were 55 (10) and 10 (03) years. Optimal glucose and LDL control were achieved by 30% and 62%, and 23% had achieved both. Regression analysis revealed significant association of self-reported high dietary compliance with achievement of both targets.
Findings highlight the suboptimal glucose and lipid control among patients with diabetes. Significant association of better dietary compliance with control of both parameters emphasizes the value of proper dietary adherence in achieving the optimal metabolic control among patients with diabetes.
在发展中国家,糖尿病患者的饮食和药物依从性对实现最佳代谢(血糖和血脂)控制的影响仍未得到充分研究。
从糖尿病患者中获取自我报告的饮食和药物依从性评分(0 - 10分)、糖化血红蛋白(HbA1c)以及低密度脂蛋白(LDL)水平。HbA1c < 7%和LDL < 100mg/dL分别用于定义最佳血糖和血脂控制。估算达到每个以及同时达到两个最佳参数的比例。采用回归分析研究年龄、性别、发病年龄、糖尿病病程、自我报告的饮食和药物依从性评分与两个参数达成情况之间的关联。
207例患者的糖尿病平均(标准差)年龄和病程分别为55(10)岁和10(03)年。30%的患者实现了最佳血糖控制,62%的患者实现了最佳LDL控制,23%的患者两者均实现。回归分析显示,自我报告的高饮食依从性与两个目标的达成存在显著关联。
研究结果凸显了糖尿病患者血糖和血脂控制欠佳的情况。更好的饮食依从性与两个参数的控制之间存在显著关联,强调了在糖尿病患者中实现最佳代谢控制时保持适当饮食依从性的价值。