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舒更葡糖钠致小儿患者过敏反应

Sugammadex-Induced Hypersensitivity Reaction in a Pediatric Patient.

作者信息

Çolak Alkin, Yılmaz Elif, Kıray Büşra Küçük

机构信息

Department of Anaesthesiology, Trakya University School of Medicine, Edirne, Turkey.

Department of Anaesthesiology, Edirne Sultan I. Murat Government Hospital, Edirne, Turkey.

出版信息

Turk J Anaesthesiol Reanim. 2018 Feb;46(1):66-68. doi: 10.5152/TJAR.2018.04696. Epub 2018 Feb 1.

Abstract

We report a case of a 3-year-old boy who administered sugammadex and developed an allergic reaction several minutes after the administration. He developed an increase in airway pressures and a decrease in peripheral oxygen saturation; auscultation revealed widespread wheezing in the lungs. He was successfully treated with immediate administration of methylprednisolone, pheniramine, and theophylline. We assumed an allergic reaction to sugammadex based on the clinical condition of the patient.

摘要

我们报告一例3岁男孩,其在给予舒更葡糖钠后几分钟出现过敏反应。他出现气道压力升高和外周血氧饱和度下降;听诊显示双肺广泛哮鸣音。通过立即给予甲泼尼龙、苯海拉明和茶碱,他得到了成功治疗。基于患者的临床情况,我们推测为对舒更葡糖钠的过敏反应。

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Sugammadex-Induced Hypersensitivity Reaction in a Pediatric Patient.舒更葡糖钠致小儿患者过敏反应
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Hypersensitivity reaction probably induced by sugammadex.可能由舒更葡糖钠引起的超敏反应。
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本文引用的文献

2
Clinical pharmacology and efficacy of sugammadex in the reversal of neuromuscular blockade.舒更葡糖钠逆转神经肌肉阻滞的临床药理学及疗效
Expert Opin Drug Metab Toxicol. 2016 Sep;12(9):1097-108. doi: 10.1080/17425255.2016.1215426. Epub 2016 Aug 3.
4
Three suspected cases of sugammadex-induced anaphylactic shock.三例疑似舒更葡糖钠所致过敏性休克病例。
BMC Anesthesiol. 2014 Oct 17;14:92. doi: 10.1186/1471-2253-14-92. eCollection 2014.
6
Sugammadex hypersensitivity-a case of anaphylaxis.舒更葡糖钠超敏反应——1例过敏反应病例
Anaesth Intensive Care. 2014 Jan;42(1):89-92. doi: 10.1177/0310057X1404200115.
8
Hypersensitivity reaction probably induced by sugammadex.可能由舒更葡糖钠引起的超敏反应。
Acta Anaesthesiol Taiwan. 2012 Dec;50(4):183-4. doi: 10.1016/j.aat.2012.08.010. Epub 2013 Jan 5.

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