囊肿液生物标志物——胰腺囊性病变恶性肿瘤的诊断与预测
Cyst Fluid Biomarkers - Diagnosis and Prediction of Malignancy for Cystic Lesions of the Pancreas.
作者信息
Raman Aadhithya, Lennon Anne Marie
机构信息
Department of Medicine, Surgery, Radiology and Oncology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
出版信息
Visc Med. 2018 Jul;34(3):178-181. doi: 10.1159/000490137. Epub 2018 Jun 13.
Abstract
Pancreatic cysts are common, and are identified in 2-13% of individuals undergoing cross-sectional imaging. Intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs) are pancreatic cysts which are precursors to pancreatic adenocarcinoma. Currently available tools are imperfect at differentiating IPMNs and MCNs from other, benign types of pancreatic cysts. The role of molecular markers in the evaluation of pancreatic cysts and the identification of cysts with high-grade dysplasia or invasive adenocarcinoma is reviewed.
摘要
胰腺囊肿很常见，在接受横断面成像检查的个体中，有2% - 13%被发现患有此病。导管内乳头状黏液性肿瘤（IPMNs）和黏液性囊性肿瘤（MCNs）是胰腺囊肿，是胰腺腺癌的癌前病变。目前可用的工具在区分IPMNs和MCNs与其他良性类型的胰腺囊肿方面并不完善。本文综述了分子标志物在胰腺囊肿评估以及识别高级别发育异常或浸润性腺癌囊肿中的作用。
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