Ngamruengphong Saowanee, Lennon Anne Marie
Division of Gastroenterology and Hepatology, The Johns Hopkins Medical Institutions, 1800 Orleans Street, Sheikh Zayed Tower, Baltimore, MD 21287, USA.
Division of Gastroenterology and Hepatology, The Johns Hopkins Medical Institutions, 1800 Orleans Street, Sheikh Zayed Tower, Room 7125JB3, Baltimore, MD 21287, USA.
Surg Pathol Clin. 2016 Dec;9(4):677-684. doi: 10.1016/j.path.2016.05.010.
Pancreatic cysts are extremely common, and are identified in between 2% to 13% on abdominal imaging studies. Most pancreatic cysts are pseudocysts, serous cystic neoplasms, mucinous cystic neoplasms, or intraductal papillary mucinous neoplasms. The management of pancreatic cysts depends on whether a cyst is benign, has malignant potential, or harbors high-grade dysplasia or invasive carcinoma. The diagnosis of pancreatic cysts, and assessment of risk of malignant transformation, incorporates clinical history, computed tomography (CT), magnetic resonance imaging (MRI), endoscopic ultrasound, and fine-needle aspiration of cyst fluid. This article reviews the cyst fluid markers that are currently used, as well as promising markers under development.
胰腺囊肿极为常见，在腹部影像学检查中发现率为2%至13%。大多数胰腺囊肿为假性囊肿、浆液性囊性肿瘤、黏液性囊性肿瘤或导管内乳头状黏液性肿瘤。胰腺囊肿的处理取决于囊肿是良性、具有恶变潜能、存在高级别异型增生还是浸润性癌。胰腺囊肿的诊断以及恶变风险评估包括临床病史、计算机断层扫描（CT）、磁共振成像（MRI）、内镜超声以及囊肿液细针穿刺。本文综述了目前使用的囊肿液标志物以及正在研发的有前景的标志物。
