Hasselbacher K, Bruchhage K-L, Abrams N, Steffen A
Klinik für Hals‑, Nasen- und Ohrenheilkunde, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Universität zu Lübeck, Ratzeburger Allee, 23538, Lübeck, Deutschland.
HNO. 2018 Nov;66(11):837-842. doi: 10.1007/s00106-018-0550-1.
First-line treatment for patients with obstructive sleep apnea (OSA) is continuous positive airway pressure (CPAP) therapy. However, many patients cannot use CPAP sufficiently. With drug-induced endoscopy (DISE), it is possible to assess the collapse pattern in the upper airway. The aim of this work was to evaluate a collective of patients with CPAP usage problems using DISE, in order to evaluate their usage problems and therapy recommendations.
Over a period of 5 years, all patients with an apnea-hypopnea index (AHI) of at least 15/h were retrospectively evaluated using DISE. The recommended treatment options were then analyzed.
Data analysis of 210 patients showed that about two thirds reported mask problems as the cause of non-adherence to CPAP. A complete concentric collapse (CCC) could be excluded in 75%. These patients had a lower AHI and more frequent tonsillectomy (TE) than patients with CCC. Double the number of patients with a body mass index (BMI) > 35 kg/m had a CCC compared to those with a BMI < 35 kg/m. Among patients with similar BMI and AHI, CCC was twice as likely to be found in patients without TE.
The course of treatment recommended for OSA often differs, depending on CCC, BMI > 35 kg/m, and previous TE.
阻塞性睡眠呼吸暂停(OSA)患者的一线治疗方法是持续气道正压通气(CPAP)治疗。然而,许多患者无法充分使用CPAP。通过药物诱导内镜检查(DISE),可以评估上气道的塌陷模式。这项工作的目的是使用DISE评估一组存在CPAP使用问题的患者,以评估他们的使用问题并提出治疗建议。
在5年的时间里,对所有呼吸暂停低通气指数(AHI)至少为15次/小时的患者进行回顾性DISE评估。然后分析推荐的治疗方案。
对210例患者的数据分析表明,约三分之二的患者报告面罩问题是导致不坚持使用CPAP的原因。75%的患者可排除完全同心塌陷(CCC)。与有CCC的患者相比,这些患者的AHI较低,扁桃体切除术(TE)更频繁。体重指数(BMI)>35kg/m²的患者中CCC的数量是BMI<35kg/m²患者的两倍。在BMI和AHI相似的患者中,未接受TE的患者出现CCC的可能性是接受TE患者的两倍。
对于OSA推荐的治疗过程通常因CCC、BMI>35kg/m²和既往TE而有所不同。