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睡眠内镜检查中软腭完全同心性塌陷:持续气道正压通气(CPAP)治疗失败的患者接受悬雍垂腭咽成形术(UPPP)后可能会有哪些变化?

Complete concentric collapse at the soft palate in sleep endoscopy: what change is possible after UPPP in patients with CPAP failure?

作者信息

Hasselbacher Katrin, Seitz A, Abrams N, Wollenberg B, Steffen A

机构信息

Department of Otorhinolaryngology, University of Lübeck, Ratzeburger Allee, 23538, Lübeck, Germany.

出版信息

Sleep Breath. 2018 Dec;22(4):933-938. doi: 10.1007/s11325-018-1657-z. Epub 2018 May 16.

Abstract

PURPOSE

The aim of this work was to assess whether uvulopalatopharyngoplasty in patients with failure for positive airway pressure not only reduces the degree of obstructive sleep apnea but also to determine as well if it changes the collapse pattern of the soft palate and thereby fulfills the qualifications for implementing upper airway stimulation (UAS) as an adjunctive solution.

METHOD

Fifteen patients with intolerance for positive airway pressure were included in this retrospective cohort study. Polygraphy and drug-induced sleep endoscopy were used in order to evaluate the reduction of the apnea-hypopnea index (AHI), as well as the change of collapse pattern at the soft palate level before and about 3 months after uvulopalatopharyngoplasty and tonsillectomy (TE-UPPP).

RESULTS

In 93% of the patients, a postoperative change of the initially complete concentric palatal collapse pattern could be found during drug-induced sleep endoscopy. In one patient, no obstruction at all was seen at the soft palatal level. Only one patient still presented with a complete concentric collapse at velum level. AHI decreased from mean 34.7 events per hour to 20.2/h and oxygen desaturation index from 25.3 events per hour to 16.1/h.

CONCLUSION

Patients seeking for positive airway pressure alternatives could not only benefit from reduction of AHI by TE-UPPP postoperatively; additionally, by changing the collapse pattern at the soft palate, they might also fulfill criteria for upper airway stimulation (UAS) in case of persistent OSA of at least moderate degree.

摘要

目的

本研究旨在评估对于持续气道正压通气治疗效果不佳的患者,悬雍垂腭咽成形术是否不仅能降低阻塞性睡眠呼吸暂停的程度,还能确定其是否改变软腭的塌陷模式,从而满足实施上气道刺激(UAS)作为辅助治疗方案的条件。

方法

本回顾性队列研究纳入了15例对持续气道正压通气不耐受的患者。使用多导睡眠监测和药物诱导睡眠内镜检查,以评估悬雍垂腭咽成形术联合扁桃体切除术(TE-UPPP)术前及术后约3个月时呼吸暂停低通气指数(AHI)的降低情况,以及软腭水平塌陷模式的变化。

结果

在93%的患者中,药物诱导睡眠内镜检查发现术后最初完全同心的腭部塌陷模式发生了改变。1例患者在软腭水平未见任何阻塞。仅1例患者在腭帆水平仍呈现完全同心塌陷。AHI从平均每小时34.7次事件降至20.2次/小时,氧饱和度下降指数从每小时25.3次事件降至16.1次/小时。

结论

寻求持续气道正压通气替代方案的患者不仅可以从TE-UPPP术后AHI降低中获益;此外,通过改变软腭的塌陷模式,对于至少中度的持续性阻塞性睡眠呼吸暂停患者,他们可能也满足上气道刺激(UAS)的标准。

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