Shen K, Gongloff R K
J Prosthet Dent. 1986 Jul;56(1):65-70. doi: 10.1016/0022-3913(86)90285-4.
HA has been used successfully as a hard tissue graft in alveolar ridge augmentation; however, its particulate nature limits its application to select cases. A study in rats was done to examine the feasibility of a combined system of HA encased in collagen film as a hard tissue graft. Gross, radiographic, and histologic examination showed that collagen film helped to shape and contain the HA particulate during healing for as long as 4 weeks. The collagen did not interfere with the normal tissue response around the HA particulate.