Bourusly Maha J, Burahma Muna H, Khalifa Nisreen, Motti Hubert, Kaleefa Sahar, Adil Mohammad, Alanzi Suad, Alshazli Medhat
Pediatric Hematology and Oncology, National Bank of Kuwait Specialized Hospital for Children, Sabah, KWT.
Pediatrics, National Bank of Kuwait Specialized Hospital for Children, Sabah, KWT.
Cureus. 2021 Feb 13;13(2):e13333. doi: 10.7759/cureus.13333.
Background and objective There is a lack of updated data regarding pediatric cancer in Kuwait, with no separate childhood cancer registry available in the country prior to this study. We aimed to determine the trends in different cancer types with respect to international statistics, in order to understand their nature and identify gaps in their diagnosis and management. Methods This retrospective study was based on data obtained from the first national childhood cancer registry of the National Bank of Kuwait (NBK) Specialized Hospital for Children, the only hospital that manages pediatric cancer patients in Kuwait. The registry included the data of all children with cancer in Kuwait from 2004 to 2017 and had complete data files. Findings The total number of patients in the childhood cancer registry was 1,387. A total of 1,009 files met our eligibility criteria. In 2017, the incidence of childhood leukemia was determined to be six per 100,000 people, and for other cancers, it was 12.6 per 100,000 people. The most common cancer was leukemia (457 patients), followed by lymphoma (141 patients), and brain tumors (92 patients). The majority of children received chemotherapy (n=891, 88.3%). Post induction or treatment, the majority of patients achieved complete remission (n=790, 78.3%). The overall survival rate of children with cancer was around 80%. Major complications developed in 9% of patients. Conclusion These findings highlight the importance of hospital-based cancer registries. Active data management programs are essential to monitor outcomes, measure the effectiveness of current practice, and improve the quality of care.
背景与目的 科威特缺乏关于儿童癌症的最新数据，在本研究之前该国没有单独的儿童癌症登记处。我们旨在确定不同癌症类型相对于国际统计数据的趋势，以了解其性质并找出诊断和管理方面的差距。方法 这项回顾性研究基于从科威特国家银行（NBK）儿童医院获得的首个全国儿童癌症登记处的数据，该医院是科威特唯一管理儿童癌症患者的医院。该登记处包括2004年至2017年科威特所有癌症患儿的数据且数据文件完整。结果 儿童癌症登记处的患者总数为1387人。共有1009份文件符合我们的纳入标准。2017年，儿童白血病发病率确定为每10万人中有6例，其他癌症发病率为每10万人中有12.6例。最常见的癌症是白血病（457例患者），其次是淋巴瘤（141例患者）和脑肿瘤（92例患者）。大多数儿童接受了化疗（n = 891，88.3%）。诱导治疗或治疗后，大多数患者实现了完全缓解（n = 790，78.3%）。癌症患儿的总体生存率约为80%。9%的患者出现了严重并发症。结论 这些发现凸显了基于医院的癌症登记处的重要性。积极的数据管理计划对于监测结果、衡量当前实践的有效性以及提高护理质量至关重要。
