Skalny A V, Simashkova N V, Skalnaya M G, Klyushnik T P, Chernova L N, Tinkov A A
Peoples Friendship University of Russia, Moscow, Russia; Russian Research Institute of Medicinal and Aromatic Plants, Moscow, Russia; Yaroslavl State University, Yaroslavl, Russia; Trace Element Institute of UNESCO, Lyon, France.
Mental Health Research Center, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(5. Vyp. 2):75-79. doi: 10.17116/jnevro20181185275.
The authors present a review of literature on the involvement of perinatal and postnatal mercury exposure in the pathogenesis of autistic spectrum disorders (ASD). A number of studies have shown a reliable association between perinatal and postnatal exposure to mercury and ASD development aa well as clinical and laboratory markers of the severity of these disorders. However the association was not confirmed in other studies. Such contradictions may be explained by differences in the composition of study groups, including geographical characteristics, and the influence of the factors related to mercury neurotoxicity.
作者对围产期和产后汞暴露与自闭症谱系障碍（ASD）发病机制相关的文献进行了综述。多项研究表明，围产期和产后汞暴露与ASD的发展以及这些疾病严重程度的临床和实验室指标之间存在可靠的关联。然而，其他研究并未证实这种关联。这种矛盾可能是由于研究组构成的差异，包括地理特征，以及与汞神经毒性相关因素的影响。
