Jamshidian-Tehrani Mansooreh, Nekoozadeh Shahbaz, Alami Elham, Ghadimi Hadi, Nabavi Amin, Ameli Kambiz, Sharif Kashani Shervin, Kashkouli Mohsen Bahmani, Sadeghi-Tari Ali
a Eye Research Center, Farabi Eye Hospital , Tehran University of Medical Sciences , Tehran , Iran.
b Eye Research Center, Rassoul Akram Hospital , Iran University of Medical Sciences , Tehran , Iran.
Orbit. 2019 Jun;38(3):173-179. doi: 10.1080/01676830.2018.1513537. Epub 2018 Aug 24.
: To measure alterations in orbital blood flow parameters using color Doppler imaging (CDI) before and after orbital decompression in patients with moderate to severe thyroid eye disease (TED). : Resistance index (RI) and maximum and minimum velocity of ophthalmic artery (OA), superior ophthalmic vein (SOV), and central retinal artery (CRA) of 24 eyes (14 patients) with TED were measured before and at least 3 months after cosmetic orbital decompression procedure (single or double walls) using CDI. Complete eye examination was performed to define the severity (EUGOGO classification) and activity (clinical activity score) of TED. : Median OA ( = 0.003) and CRA ( = 0.001) resistance indices were significantly reduced postoperatively. Significant differences were found in maximum ( = 0.001) and minimum ( = 0.014) velocity of SOV before and after surgery. While a significant decrease in exophthalmometry was observed after the orbital decompression ( = 0.031), intraocular pressure changes were not significant ( = 0.182). : Orbital decompression procedure led to a significant reduction of RI in both CRA and OA in patients with TED.
使用彩色多普勒成像（CDI）测量中度至重度甲状腺眼病（TED）患者眼眶减压前后眼眶血流参数的变化。
对24只眼（14例患者）的TED患者，在进行美容性眼眶减压手术（单壁或双壁）前及术后至少3个月，使用CDI测量眼动脉（OA）、眼上静脉（SOV）和视网膜中央动脉（CRA）的阻力指数（RI）以及最大和最小流速。进行全面的眼部检查以确定TED的严重程度（EUGOGO分类）和活动度（临床活动评分）。
术后OA（P = 0.003）和CRA（P = 0.001）的阻力指数中位数显著降低。手术前后SOV的最大流速（P = 0.001）和最小流速（P = 0.014）存在显著差异。虽然眼眶减压后眼球突出度显著降低（P = 0.031），但眼压变化不显著（P = 0.182）。
眼眶减压手术导致TED患者CRA和OA的RI显著降低。
