Leskov V P, Larin B S, Mardynskiĭ Iu S
Med Radiol (Mosk). 1986 Jun;31(6):7-11.
The paper is concerned with the results of gamma-beam therapy of 120 patients with inoperable lung cancer using the fractionation of a common daily dose of 2-2.2 Gy into 2 equal fractions as a variant of super-fractionated irradiation used in clinical practice. The direct and short-term therapeutic results were improved: a complete tumor regression rate determined by x-ray was 26.7%, a 2-year survival rate 19.2%. In the group of patients who were irradiated by the commonly used methods, the same values were lower. Improved tolerance of therapy with fractionation of a common daily dose was noted.
本文关注的是120例无法手术的肺癌患者采用伽马射线治疗的结果,即将常规每日剂量2 - 2.2 Gy分为2个相等部分作为临床实践中使用的超分割照射变体。直接和短期治疗效果得到改善:经X线测定的肿瘤完全消退率为26.7%,2年生存率为19.2%。在采用常用方法照射的患者组中,这些数值较低。注意到采用常规每日剂量分割后治疗耐受性有所改善。