[Remissions and acute toxicity during accelerated fractionated irradiation of non-small-cell bronchial carcinoma].

Accelerated fractionation (total dose 66 Gy, single dose 1.8 to 2 Gy, 1 to 2 fractions daily, total treatment period 4 to 5.5 weeks) brings about more than 40% of complete remissions and more than 90% of objective remissions (assessed by radiology) of non-small cell bronchogenic carcinomas. Tumor-induced symptoms are improved in more than 90%. A treatment period of less than four weeks causes considerable acute (and persistent) oesophageal reactions. In case of a treatment period of more than five weeks there is no substantial increase of toxicity.