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[非小细胞支气管癌加速分割照射期间的缓解情况及急性毒性]

[Remissions and acute toxicity during accelerated fractionated irradiation of non-small-cell bronchial carcinoma].

作者信息

von Rottkay P

出版信息

Strahlenther Onkol. 1986 May;162(5):300-7.

PMID:3715709
Abstract

Accelerated fractionation (total dose 66 Gy, single dose 1.8 to 2 Gy, 1 to 2 fractions daily, total treatment period 4 to 5.5 weeks) brings about more than 40% of complete remissions and more than 90% of objective remissions (assessed by radiology) of non-small cell bronchogenic carcinomas. Tumor-induced symptoms are improved in more than 90%. A treatment period of less than four weeks causes considerable acute (and persistent) oesophageal reactions. In case of a treatment period of more than five weeks there is no substantial increase of toxicity.

摘要

加速分割放疗(总剂量66 Gy,单次剂量1.8至2 Gy,每日1至2次分割,总治疗期4至5.5周)可使非小细胞支气管癌的完全缓解率超过40%,客观缓解率(通过放射学评估)超过90%。超过90%的肿瘤引起的症状得到改善。治疗期少于四周会导致相当严重的急性(和持续性)食管反应。治疗期超过五周时,毒性没有显著增加。

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[Remissions and acute toxicity during accelerated fractionated irradiation of non-small-cell bronchial carcinoma].[非小细胞支气管癌加速分割照射期间的缓解情况及急性毒性]
Strahlenther Onkol. 1986 May;162(5):300-7.
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引用本文的文献

1
Non-small cell lung cancer and CHART (continuous hyperfractionated accelerated radiotherapy)--where do we stand?非小细胞肺癌与CHART(连续超分割加速放疗)——我们目前的进展如何?
Ulster Med J. 2000 Nov;69(2):128-36.