Lauffer H, Wenzel D
Neuropediatrics. 1986 May;17(2):72-4. doi: 10.1055/s-2008-1052504.
To investigate the age-dependency of central conduction time somatosensible evoked potentials to median nerve stimulation were recorded in 80 infants and children from the age of one week to 20 years. It is shown that the central conduction time starts at about 14 ms in the neonatal period and then gradually declines until the 7th or 8th year of life to the normal adult value with an upper limit of 7 ms. By dividing the data into several groups with age delimiters at 0.5, 1, 3, 5 and 7 years it shows significant differences of the mean values for the central conduction times according to the Student's t-test. The graph itself can well be approximated by the exponential regression y = 6.099 + 7.55 X e-0.686 X x where y represents the CCT and x the age in years. This slow maturation kinetic is presumably due to the ongoing central myelinisation.
为研究正中神经刺激体感诱发电位的中枢传导时间与年龄的相关性，对80名年龄从1周大至20岁的婴幼儿及儿童进行了记录。结果显示，中枢传导时间在新生儿期约为14毫秒，随后逐渐下降，直至7至8岁时达到正常成人水平，上限为7毫秒。通过将数据按0.5岁、1岁、3岁、5岁和7岁的年龄分界点分为几组，根据学生t检验，中枢传导时间的平均值存在显著差异。该曲线本身可以很好地用指数回归方程y = 6.099 + 7.55×e^(-0.686×x)来近似，其中y代表中枢传导时间（CCT），x代表年龄（岁）。这种缓慢的成熟动力学可能是由于中枢髓鞘形成仍在进行。
