Sitzoglou C, Fotiou F
Neuropediatrics. 1985 Nov;16(4):205-8. doi: 10.1055/s-2008-1059538.
We investigated the somatosensory evoked potentials (SSEPs) in 62 healthy children, ten days to twelve years old. Our control group consisted of ten healthy adults, sixteen to thirty-six years old. The stimulus was applied at the median nerve at the wrist and the cerebral SSEPs were recorded by electrodes placed on the contralateral parietal scalp region, while for the cervical SSEP recording the electrodes were placed over the skin at the C6-C7 vertebral region. The reference electrode was placed at the FZ according to the 10-20 system. Our study revealed a significant change in the early components of the SSEPs (NI and PI) between groups of different ages. The latency and duration of the NI wave form and the latency of PI were inversely correlated with age. These changes in the early components of the SSEPs are most likely due to the gradual maturation of the afferent nervous system with age. From the difference in latencies between the peak of NI and the cervical SSEP we were able to calculate the sensory conduction time in the central nervous system and found a progressive decrease in relation to the increase of age. This is most likely due to the development of postnatal myelination of the sensory fibres of the central somatosensory pathway.
我们对62名年龄在10天至12岁的健康儿童进行了体感诱发电位（SSEPs）研究。我们的对照组由10名年龄在16至36岁的健康成年人组成。刺激施加于手腕处的正中神经，通过放置在对侧顶叶头皮区域的电极记录大脑SSEPs，而对于颈部SSEP记录，电极放置在C6 - C7椎体区域的皮肤上。参考电极根据10 - 20系统放置在FZ处。我们的研究揭示了不同年龄组之间SSEPs早期成分（NI和PI）的显著变化。NI波形的潜伏期和持续时间以及PI的潜伏期与年龄呈负相关。SSEPs早期成分的这些变化很可能是由于传入神经系统随年龄逐渐成熟所致。根据NI峰值与颈部SSEP之间潜伏期的差异，我们能够计算出中枢神经系统中的感觉传导时间，并发现其与年龄增长呈逐渐下降的关系。这很可能是由于中枢体感通路感觉纤维出生后髓鞘形成的发育所致。
