D'Hondt E, Berge E, Colinet G, Duchene M, Peetermans J
Postgrad Med J. 1985;61 Suppl 4:53-6.
The Smith Kline-RIT live attenuated Oka-strain varicella vaccine (Varilrix) is manufactured following the seed lot principle, with each vaccine lot derived from the same working seed. Production of the vaccine basically consists in the multiplication of the working seed under standardized, well-defined conditions guaranteeing consistency of the vaccine lots. Quality control tests, determining the vaccine's purity, safety, potency, and efficacy, are carried out at each defined stage of the production process.
史克必成公司的减毒活Oka株水痘疫苗（Varilrix）是按照种子批原则生产的，每批疫苗都来源于同一工作种子。该疫苗的生产基本上是在标准化、明确界定的条件下繁殖工作种子，以确保各批疫苗的一致性。在生产过程的每个规定阶段都要进行质量控制测试，以确定疫苗的纯度、安全性、效力和有效性。
