Roche Bastien, Simon Anne-Laure, Guilmin-Crépon Sophie, Boizeau Priscilla, Andriss Béatrice, Alberti Corinne, Presedo Ana, Ilharreborde Brice, Husson Isabelle
Assistance Publique des Hôpitaux de Paris (AP-HP), Robert Debré University Hospital, Gait and Motion Analysis Laboratory, France.
Assistance Publique des Hôpitaux de Paris (AP-HP), Robert Debré University Hospital, Gait and Motion Analysis Laboratory, France; AP-HP, Robert Debré University Hospital, Pediatric Orthopaedic Surgery Department, France.
Gait Posture. 2018 Oct;66:45-50. doi: 10.1016/j.gaitpost.2018.08.017. Epub 2018 Aug 20.
Friedreich ataxia (FRDA) affects the spatio-temporal parameters (STP) of gait. To our knowledge, proper tools to measure the variability of ataxic gait have not been validated yet. The aims of the present study were: (1) to measure the reproducibility of STP and gait scores in young patients with FRDA and (2) to describe the characteristics of gait parameters in this population.
Thirty-six patients (18 males, 18 females) with diagnosis of FRDA (mean age 16.4 ± 4.5 years) were asked to walk barefoot at a self-selected pace along the pressure sensitive walkway (GAITRite). Three trials were recorded for each patient and repeated 48 h later. Collected data was put into statistical analysis tests to determine reliability and variability of STPs and two other gait scores: The Functional Ambulation Performance score (FAP) and the Gait Variability Index (GVI).
All STPs showed strong or very strong reliability (ICC > 0.7) and a low variability. The two parameters showing the lowest reliability (0.71 and 0.74) were the base of support and the foot progression angle. The FAP score and the GVI showed strong reliability (ICC > 0.8).
The GAITRite system allows feasible and reliable measurements of gait parameters in young patients with FRDA. Lower reliability found for the weakest parameters was attributed to the software automatic errors and the ankle laxity noted in every patient.
弗里德赖希共济失调（FRDA）会影响步态的时空参数（STP）。据我们所知，尚未验证用于测量共济失调步态变异性的合适工具。本研究的目的是：（1）测量FRDA年轻患者STP和步态评分的可重复性，以及（2）描述该人群的步态参数特征。
36例确诊为FRDA的患者（18例男性，18例女性）（平均年龄16.4±4.5岁）被要求沿着压力感应步道（GAITRite）以自选速度赤脚行走。为每位患者记录三次试验，并在48小时后重复进行。将收集到的数据进行统计分析测试，以确定STP以及另外两个步态评分的可靠性和变异性：功能性步行能力评分（FAP）和步态变异性指数（GVI）。
所有STP均显示出强或非常强的可靠性（ICC>0.7）且变异性较低。可靠性最低的两个参数（0.71和0.74）是支撑基底和足部前进角度。FAP评分和GVI显示出强可靠性（ICC>0.8）。
GAITRite系统能够对FRDA年轻患者的步态参数进行可行且可靠的测量。最弱参数的较低可靠性归因于软件自动错误以及在每位患者中都观察到的踝关节松弛。
