The Warren Alpert Medical School of Brown University, 222 Richmond Street, Providence, RI 02903, USA; Accreditation Council for Graduate Medical Education, 401 North Michigan Avenue, Suite 2000, Chicago, IL 60611, USA.
Infect Dis Clin North Am. 2018 Sep;32(3):495-506. doi: 10.1016/j.idc.2018.04.001.
Infection is an inevitable complication of solid organ transplantation. Unrecognized infection may be transmitted from a donor and result in disseminated disease in the immunosuppressed host. Recent outbreaks of deceased donor-derived infections resulting in high rates of mortality and severe morbidity have emphasized the need to be cautious in using donors with possible meningoencephalitis. Screening of organ donors for potential transmissible infections is paramount to improving transplantation outcomes.
感染是实体器官移植不可避免的并发症。未被识别的感染可能由供体传播，并导致免疫抑制宿主发生播散性疾病。最近，由于供体来源的感染爆发导致高死亡率和严重发病率，因此强调需要谨慎使用可能患有脑膜炎的供体。对潜在传染性感染的器官供体进行筛查对于改善移植结果至关重要。
