Marzoian R A, Potapov A A, Pisetskaia M V
Vopr Med Khim. 1986 May-Jun;32(3):95-8.
An increase in content of beta-endorphin simultaneously with either low or high concentrations of corticotropin were observed in blood of patients with critical craniocerebral injury at the first day of the trauma. The content of beta-endorphin was increased and the content of corticotropin was decreased in blood of the patients within one day after the surgical treatment of sub-, epi- and intracerebral hematomas. No correlation between contents of beta-endorphin and corticotropin was noted. The data obtained suggest existence of various pathways for regulation of beta-endorphin synthesis and secretion, which are independent from the corticotropin regulation processes.
在颅脑损伤患者受伤第一天，观察到β-内啡肽含量增加，同时促肾上腺皮质激素浓度处于低水平或高水平。在对脑内、硬膜外和硬膜下血肿进行手术治疗后的一天内，患者血液中β-内啡肽含量增加而促肾上腺皮质激素含量降低。未发现β-内啡肽含量与促肾上腺皮质激素含量之间存在相关性。所获得的数据表明存在多种调节β-内啡肽合成和分泌的途径，这些途径独立于促肾上腺皮质激素调节过程。
