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[轻度颅脑外伤患者促肾上腺皮质激素、β-内啡肽和皮质醇的每日分泌情况]

[Profiles of daily secretion of ACTH, beta-endorphins and cortisol in patients after minor craniocerebral trauma].

作者信息

Ziaber J, Chmielewski H, Laskowski A, Radek A

机构信息

Kliniki Neurologicznej Szpitala Klinicznego WAM, Lodzi.

出版信息

Wiad Lek. 1995 Jan-Jun;48(1-12):36-9.

PMID:9638202
Abstract

In 12 men aged 20-25 men who had minor craniocerebral trauma the profiles of daily secretion of ACTH, beta-endorphin and cortisol were studied. The studies were carried out on the second day after the trauma. Plasma concentrations of the hormones were determined on 8.00, 12.00, 17.00 and 22.00 hours. Statistically significantly increased, in relation to healthy persons, (p < 0.01) values of plasma hormone concentration were found at all time points. In 50% of the patients (six cases) a disturbance was found of the profile of daily secretion of ACTH and beta-endorphin. The disturbance of the profile of cortisol secretion was found only in one patient.

摘要

对12名年龄在20至25岁之间有轻度颅脑创伤的男性,研究了促肾上腺皮质激素(ACTH)、β-内啡肽和皮质醇的每日分泌情况。研究在创伤后第二天进行。于上午8点、中午12点、下午5点和晚上10点测定血浆中这些激素的浓度。与健康人相比,所有时间点的血浆激素浓度值均有统计学显著升高(p < 0.01)。在50%的患者(6例)中,发现促肾上腺皮质激素和β-内啡肽的每日分泌情况存在紊乱。仅在1例患者中发现皮质醇分泌情况紊乱。

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