Rodríguez José Y, Morales-López Soraya E, Rodríguez Gerson J, Álvarez-Moreno Carlos A, Ocampo Walter, Cepeda Martha L, Mora-Valderrama Miguel A
Centro de Investigaciones Microbiológicas del Cesar (CIMCE), Hospital Rosario Pumarejo de Lopez, Clínica Laura Daniela, Clínica médicos LTDA, Valledupar, Colombia.
Microbiology Program Universidad Popular del Cesar, Valledupar, Colombia.
Med Mycol Case Rep. 2017 Dec 21;20:4-6. doi: 10.1016/j.mmcr.2017.12.002. eCollection 2018 Jun.
Mucormycosis caused by Apophysomyces variabilis is rarely reported in humans. A case of A. variabilis infection in an immunocompetent men after friction burns in a car accident is described. The infection presented as a rapidly progressive necrotizing infection of the skin and soft tissue, which required extensive surgical debridement and total colonic defunctioning colostomy associated with prolonged antifungal therapy. A. variabilis infection should be considered as a differential diagnosis of rapidly progressive necrotizing skin and soft tissue infections in immunocompetent individuals.
由多变阿波菲霉引起的毛霉病在人类中鲜有报道。本文描述了一例在车祸中遭受摩擦烧伤的免疫功能正常男性感染多变阿波菲霉的病例。该感染表现为皮肤和软组织的快速进行性坏死性感染,需要进行广泛的手术清创以及与长期抗真菌治疗相关的全结肠去功能化结肠造口术。对于免疫功能正常个体的快速进行性坏死性皮肤和软组织感染,应考虑将多变阿波菲霉感染作为鉴别诊断之一。