一名免疫功能正常儿童由多变犁头霉引起的侵袭性皮肤接合菌病
Aggressive cutaneous zygomycosis caused by Apophysomyces variabilis in an immunocompetent child.
作者信息
Al-Zaydani Ibrahim A, Al-Hakami Ahmed M, Joseph Martin R P, Kassem Walid M, Almaghrabi Mohamed K, Nageeb Abdalla, Hamid Mohamed E
机构信息
Department of Pediatrics, Aseer Central Hospital, Abha, Kingdom of Saudi Arabia.
Department of Clinical Microbiology and Parasitology, College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia.
出版信息
Med Mycol Case Rep. 2015 Dec 13;10:11-3. doi: 10.1016/j.mmcr.2015.12.003. eCollection 2015 Dec.
A zygomycetous fungus was observed in a biopsy of a 9-year-old male. The patient was presented with severe cutaneous lesions subsequent to a traumatic car accident. Following fungal detection, antifungal treatment was prescribed but condition deteriorated rapidly and above knee amputation was done as lifesaving and to control fungal infection. Analysis of the 28 S rRNA gene (accession KT149770) aligned the isolate with members of the genus Apophysomyces and the pathogen was identified as Apophysomces variabilis.
在一名9岁男性的活检中发现了一种接合菌纲真菌。该患者在一场严重的车祸后出现了严重的皮肤损伤。真菌检测后，给予了抗真菌治疗，但病情迅速恶化，为挽救生命并控制真菌感染，进行了膝上截肢手术。对28 S rRNA基因（登录号KT149770）的分析表明，该分离株与顶孢霉属的成员一致，病原体被鉴定为变异顶孢霉。
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