[系统性红斑狼疮合并多发性骨髓瘤。两例报告]

[Multiple myeloma in systemic lupus erythematosus. Report of two cases].

作者信息

Castro Irene, Arroyo S Consuelo, Yáñez Valentina, Cabezas Claudia

机构信息

Departamento de Medicina Interna, Universidad de Concepción, Concepción, Chile.

Facultad de Medicina, Universidad de Concepción, Concepción, Chile.

出版信息

Rev Med Chil. 2018 May;146(5):670-674. doi: 10.4067/s0034-98872018000500670.

DOI:10.4067/s0034-98872018000500670

PMID:30148932

Abstract

There is an increased incidence of hematological malignancies, particularly non-Hodgkin lymphoma (NHL) in systemic lupus erythematosus (SLE). In contrast, the concurrence with Multiple Myeloma (MM) is very rare, and the possible pathogenetic mechanisms underlying this association remain unclear. We report two patients who developed MM 15 and four years after being diagnosed as having SLE.

摘要

系统性红斑狼疮（SLE）患者血液系统恶性肿瘤的发病率增加，尤其是非霍奇金淋巴瘤（NHL）。相比之下，与多发性骨髓瘤（MM）同时发生的情况非常罕见，这种关联潜在的发病机制仍不清楚。我们报告了两名在被诊断为SLE后15年和4年发生MM的患者。