Gerstein Wendy, Colombo Elizabeth, Harji Farzana
Department of Medicine, New Mexico VA Health Care System, Albuquerque, New Mexico, USA.
Department of Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
BMJ Case Rep. 2018 Aug 27;2018:bcr-2018-224682. doi: 10.1136/bcr-2018-224682.
A 69-year-old man developed left knee hardware infection after suffering from an infected ingrown toenail. The hardware was removed and he was treated with intravenous vancomycin. Ten days after initiation of vancomycin, he developed severe thrombocytopaenia, epistaxis and petechiae. Vancomycin was discontinued, and platelets rapidly recovered. Serum vancomycin IgG were positive. Patient completed a 6-week course of ceftriaxone with no further complications.
一名69岁男性在患有感染性嵌甲后发生左膝内固定装置感染。取出内固定装置后，他接受了静脉注射万古霉素治疗。使用万古霉素10天后，他出现了严重的血小板减少、鼻出血和瘀点。停用万古霉素后，血小板迅速恢复。血清万古霉素IgG呈阳性。患者完成了为期6周的头孢曲松治疗，未出现进一步并发症。
