Kreska Zita, Németh Balázs, Kiss István, Péter Iván, Ajtay Zénó, Hejjel László
Zsigmondy Vilmos SPA Hospital, Harkány, Hungary.
Department of Public Health Medicine, Medical School, University of Pécs, Pécs, Hungary.
In Vivo. 2018 Sep-Oct;32(5):1259-1264. doi: 10.21873/invivo.11374.
BACKGROUND: The aim of this study was to investigate the effects of carbon-dioxide treatment on heart rate variability (HRV) parameters: mean RR interval (RRI), standard deviation of RR intervals (SDNN), root mean square of successive RR differences (RMSSD); and Porta and Guzik indices, as measures of heart rate asymmetry. MATERIALS AND METHODS: Twenty patients were enrolled (mean±SD, age=59±7.8 years). Measurements were performed before CO treatment, at the beginning of treatment, at 15 min of treatment, immediately after and 1 h after the treatment. RESULTS: Significant increase in SDNN was found 1 h after the treatment when compared to that before it (p=0.011). There were no significant changes in other parameters. CONCLUSION: CO treatment can influence the autonomic nervous system identified by SDNN changes. However, larger studies are required to confirm these results.
背景：本研究旨在探讨二氧化碳治疗对心率变异性（HRV）参数的影响：平均RR间期（RRI）、RR间期标准差（SDNN）、连续RR差值的均方根（RMSSD）；以及作为心率不对称性测量指标的波尔塔和古齐克指数。 材料与方法：招募了20名患者（平均±标准差，年龄=59±7.8岁）。在二氧化碳治疗前、治疗开始时、治疗15分钟时、治疗后即刻和治疗后1小时进行测量。 结果：与治疗前相比，治疗后1小时发现SDNN显著增加（p=0.011）。其他参数无显著变化。 结论：二氧化碳治疗可通过SDNN变化影响自主神经系统。然而，需要更大规模的研究来证实这些结果。
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