在 Pickering 乳液中分隔不相容的串联反应，以利用智能手机实现对硝胺炸药的可视化比色检测。

Compartmentalizing Incompatible Tandem Reactions in Pickering Emulsions To Enable Visual Colorimetric Detection of Nitramine Explosives Using a Smartphone.

机构信息

State Key Laboratory of Environment-friendly Energy Materials, Sichuan Co-Innovation Center for New Energetic Materials, School of National Defense Science & Technology , Southwest University of Science and Technology , Mianyang 621010 , P. R. China.

School of Materials Science and Engineering , Southwest University of Science and Technology , Mianyang 621010 , P. R. China.

出版信息

Anal Chem. 2018 Oct 2;90(19):11665-11670. doi: 10.1021/acs.analchem.8b03331. Epub 2018 Sep 10.

DOI:10.1021/acs.analchem.8b03331

PMID:30152223

Abstract

We report a visual colorimetric assay for detection of nitramine explosives such as 1,3,5-trinitro-1,3,5-triazinane (RDX) and 1,3,5,7-tetranitro-1,3,5,7-tetrazocane (HMX) using a smartphone. This assay is based on compartmentalizing incompatible tandem reactions in Pickering emulsions. The alkaline hydrolysis of RDX or HMX in one Pickering emulsion produces nitrite ions, which autodiffuse into the other Pickering emulsion to form nitrous acid. It oxidizes the 3,3',5,5'-tetramethylbenzidine (TMB) to generate yellow TMB diimine. The RGB component change of the optical images is applied to quantitatively determine the RDX and HMX at different reaction temperatures. A distinct color change occurs at RDX and HMX concentrations of 1.2 and 12 μM, respectively. The adjusted intensity increases linearly with the increase of the logarithms of the concentrations of RDX and HMX in the range of 1.2-90 μM and 12-90 μM, respectively. The limits of detection of RDX and HMX are 96 and 110 nM, respectively. Importantly, this assay is employed for the detection of RDX and HMX in real water, proving the applicability of the assay in real-world samples.

摘要

我们报道了一种使用智能手机检测硝胺炸药（如 1,3,5-三硝基-1,3,5-三嗪（RDX）和 1,3,5,7-四硝基-1,3,5,7-四氮杂环辛烷（HMX）的可视化比色分析方法。该分析方法基于在 Pickering 乳液中分隔不相容的串联反应。RDX 或 HMX 在一个 Pickering 乳液中的碱性水解产生亚硝酸盐离子，这些离子自动扩散到另一个 Pickering 乳液中形成亚硝酸。它将 3,3',5,5'-四甲基联苯胺（TMB）氧化生成黄色 TMB 二亚胺。光学图像的 RGB 成分变化用于定量确定不同反应温度下的 RDX 和 HMX。在 RDX 和 HMX 浓度分别为 1.2 和 12 μM 时，会发生明显的颜色变化。调整后的强度随 RDX 和 HMX 的浓度对数线性增加，范围分别为 1.2-90 μM 和 12-90 μM。RDX 和 HMX 的检测限分别为 96 和 110 nM。重要的是，该分析方法用于检测实际水样中的 RDX 和 HMX，证明了该分析方法在实际样品中的适用性。