State Key Laboratory of Food Science and Technology , Jiangnan University , Wuxi , Jiangsu 214122 , P. R. China.
School of Food Science and Technology , Jiangnan University , Wuxi , Jiangsu 214122 , P. R. China.
J Agric Food Chem. 2018 Sep 19;66(37):9785-9793. doi: 10.1021/acs.jafc.8b03144. Epub 2018 Sep 6.
In this study, the nano- and microsized cyclodextrin-based metal-organic frameworks (CD-MOFs) were successfully conducted using short-chain starch nanoparticles as seeds through the seed-mediated method. The morphology, size, crystal structure, thermal, and N adsorption properties of CD-MOFs prepared at different time intervals were investigated. The scanning electron microscopy results showed that the size variation from nanometer to millimeter could be controlled by crystal growth time. The CD-MOFs based on short-chain starch nanoparticle had higher crystallinity and N uptake, thus indicating that the method of seed-mediated was more facile and efficient than the previous approach. Resveratrol (Res) is a natural polyphenol compound that has anticancer and antimicrobial activities against several pathogens. However, this compound suffers from poor stability. trans-Res rapidly isomerizes when exposed under ultraviolet or visible light. The results showed that the stability of Res was substantially enhanced by its encapsulation in CD-MOF crystals.
在这项研究中，通过种子介导法成功地使用短链淀粉纳米粒子作为种子来制备纳米级和微米级的环糊精基金属有机骨架（CD-MOFs）。研究了不同时间间隔制备的 CD-MOFs 的形态、尺寸、晶体结构、热性能和 N 吸附性能。扫描电子显微镜结果表明，通过晶体生长时间可以控制尺寸从纳米到毫米的变化。基于短链淀粉纳米粒子的 CD-MOFs 具有更高的结晶度和 N 吸收能力，这表明种子介导法比以前的方法更简单、更高效。白藜芦醇（Res）是一种天然多酚化合物，对多种病原体具有抗癌和抗菌活性。然而，这种化合物的稳定性较差。在紫外线或可见光下，反式 Res 会迅速异构化。结果表明，Res 的稳定性通过其在 CD-MOF 晶体中的包封得到了显著提高。
