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全数字化 18F-FDG PET 高分辨率脑图像描绘的中枢神经系统骨髓瘤。

Central Nervous System Myelomatosis Delineated by High-Resolution Brain Images From Fully Digital 18F-FDG PET.

机构信息

Department of Nuclear Medicine.

Department of Neuroradiology, CHRU-Nancy.

出版信息

Clin Nucl Med. 2018 Oct;43(10):e372-e373. doi: 10.1097/RLU.0000000000002243.

DOI:10.1097/RLU.0000000000002243
PMID:30153147
Abstract

Central nervous system myelomatosis is uncommon and is associated with a particularly poor prognosis. PET images, from a 53-year-old man referred to a fully digital F-FDG PET for relapsed multiple myeloma, revealed high F-FDG uptakes located in the cortex and sulci of the right central area and within the meningeal envelopes of the cerebellum, the trigeminal nerves, and on the spinal canal. These particular uptakes gave evidence of a central nervous system myelomatosis subsequently confirmed by plasma cells documented in cerebrospinal fluid. Such interesting images could be obtained owing to the potential of high-resolution images provided by fully digital F-FDG PET.

摘要

中枢神经系统骨髓瘤较为罕见,且预后极差。一位 53 岁男性因复发性多发性骨髓瘤接受全数字化 F-FDG PET 检查,其 PET 图像显示右中央区域皮质和脑回以及小脑、三叉神经和椎管脑膜中有高 F-FDG 摄取。这些特殊摄取提示随后通过脑脊液中浆细胞证实了中枢神经系统骨髓瘤。由于全数字化 F-FDG PET 提供的高分辨率图像的潜力,可获得如此有趣的图像。

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