Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), École d'Orthophonie, Faculté de Médecine, Université de Montréal, Montreal, QC, Canada.
Neural Plast. 2018 Aug 1;2018:5943759. doi: 10.1155/2018/5943759. eCollection 2018.
The impact of sensorimotor strategies on aphasia recovery has rarely been explored. This paper reports on the efficacy of personalized observation, execution, and mental imagery (POEM) therapy, a new approach designed to integrate sensorimotor and language-based strategies to treat verb anomia, a frequent aphasia sign. Two participants with verb anomia were followed up in a pre-/posttherapy fMRI study. POEM was administered in a massed stimulation schedule, with personalized stimuli, resulting in significant improvement in both participants, with both trained and untrained items. Given that the latter finding is rarely reported in the literature, the evidence suggests that POEM favors the implementation of a word retrieval strategy that can be integrated and generalized. Changes in fMRI patterns following POEM reflect a reduction in the number of recruited areas supporting naming and the recruitment of brain areas that belong to the language and mirror neuron systems. The data provide evidence on the efficacy of POEM for verb anomia, while pointing to the added value of combined language and sensorimotor strategies for recovery from verb anomia, contributing to the consolidation of a word retrieval strategy that can be better generalized to untrained words. Future studies with a larger sample of participants are required to further explore this avenue.
感觉运动策略对失语症康复的影响很少被探索。本文报告了个性化观察、执行和心理意象（POEM）疗法的疗效，这是一种新的方法，旨在整合感觉运动和基于语言的策略来治疗动词命名障碍，这是一种常见的失语症症状。对两名患有动词命名障碍的参与者进行了预/后功能磁共振成像（fMRI）研究。采用集中刺激方案进行 POEM 治疗，使用个性化刺激，两名参与者都有显著改善，包括训练和未训练的项目。鉴于文献中很少有报道后者的发现，证据表明 POEM 有利于实施一种可以整合和推广的单词检索策略。POEM 后的 fMRI 模式变化反映了支持命名的募集区域数量减少，以及属于语言和镜像神经元系统的大脑区域的募集。这些数据为 POEM 治疗动词命名障碍提供了证据，同时也表明联合语言和感觉运动策略对动词命名障碍的恢复具有附加价值，有助于巩固一种可以更好地推广到未训练单词的单词检索策略。需要更多的参与者的研究来进一步探索这一途径。
