Li A Y
Zhonghua Zhong Liu Za Zhi. 1985 Nov;7(6):457-9.
This paper analyzes 77 cases of ovarian tumor in children and adolescents treated in our hospital from Jul. 1952 to Aug. 1982. All were under 20 years and the youngest was 3 years old. The incidence was 6.0% of the total patients with ovarian tumor during the same period. Of 77 cases, 54 (70.1%) were benign (10 were lost to follow-up, 43 survived and 1 died of unrelated cause), and 23 (29.9%) were malignant (4 lost and 8 died, the mortality was 34.8%). 37 (48.0%) were considered to be of germ cell origin and the rest (52.0%), non-germ cell origin. In 18 patients before menarche, 14 had germ cell tumor, but in only 3, the tumor arose from the coelomic epithelia. It was of interest to note that 1 patient, only 3 years old, had granulosa cell tumor associated precocious puberty. The initial presenting symptoms were usually an abdominal mass or lower abdominal pain. Some of the germ cell tumors and mucinous cystadenomas could reach a considerable size. The prognosis of ovarian tumor is related to the clinical stage, pathological type as well as whether the treatment is thorough or not. The diagnosis, differential diagnosis and treatment are discussed. It is emphasized that the conservation of ovarian function and the fertility should be considered under the treatment.
本文分析了1952年7月至1982年8月在我院接受治疗的77例儿童及青少年卵巢肿瘤病例。所有患者年龄均在20岁以下，最小的3岁。其发病率占同期卵巢肿瘤患者总数的6.0%。77例中，54例（70.1%）为良性（10例失访，43例存活，1例死于无关原因），23例（29.9%）为恶性（4例失访，8例死亡，死亡率为34.8%）。37例（48.0%）被认为起源于生殖细胞，其余（52.0%）起源于非生殖细胞。在18例初潮前患者中，14例患有生殖细胞肿瘤，但只有3例肿瘤起源于体腔上皮。值得注意的是，1例仅3岁的患者患有颗粒细胞瘤伴性早熟。最初的症状通常是腹部肿块或下腹部疼痛。一些生殖细胞肿瘤和黏液性囊腺瘤可长得相当大。卵巢肿瘤的预后与临床分期、病理类型以及治疗是否彻底有关。本文讨论了其诊断、鉴别诊断及治疗。强调在治疗过程中应考虑保留卵巢功能和生育能力。
