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20岁及以下儿童和青少年的卵巢肿瘤。

Ovarian tumors in children and adolescents less than 20 years age.

作者信息

Yakushiji M, Matsukuma T, Abe M, Nishida T, Nishimura H, Tsunawaki A, Kato T

出版信息

Acta Obstet Gynaecol Jpn. 1981 Jun;33(6):833-8.

PMID:7246071
Abstract

Reports are made of the analytical results of 76 cases with ovarian neoplasma under 20 years of age who had been treated at the Kurume University Hospital from January 1952. The incidence of ovarian tumors was 5.5% in all age groups, and the youngest patient was 5 years of age, the mean age being 15 years. Histologically, these tumors comprised 48 cases (63%) of germ cell origin, showing characteristically of ovarian tumors occurring in childhood and adolescence. The total 76 cases included 40 of malignant tumors, which were subdivided into 13 of embryonal carcinoma, 12 of solid teratoma, 9 of dysgerminoma, 5 of simple carcinoma, and 1 case of granulosa cell tumor. In all the cases the clinical stage was important factor for prognosis, and the prognosis of embryonal carcinoma was poorest, with only 4 cases of survival out of 13 cases. But the prognosis of dysgerminoma was comparatively good, with 8 cases of survival out of 9 cases. It is worthy of note that this tumor was highly radiosensitive, since 3 out of 4 cases at stage III and stage IV had been surviving for over 5 years.

摘要

本文报告了1952年1月至1982年12月在久留米大学医院接受治疗的76例20岁以下卵巢肿瘤患者的分析结果。卵巢肿瘤在各年龄组中的发病率为5.5%,最年轻的患者为5岁,平均年龄为15岁。组织学上,这些肿瘤包括48例(63%)生殖细胞起源的肿瘤,表现出儿童和青少年卵巢肿瘤的特征。76例患者中共有40例恶性肿瘤,其中胚胎癌13例,实性畸胎瘤12例,无性细胞瘤9例,单纯癌5例,颗粒细胞瘤1例。在所有病例中,临床分期是预后的重要因素,胚胎癌的预后最差,13例中仅有4例存活。但无性细胞瘤的预后相对较好,9例中有8例存活。值得注意的是,这种肿瘤对放疗高度敏感,因为Ⅲ期和Ⅳ期的4例患者中有3例存活超过5年。

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